2,6-吡啶二甲酰氧基烃基膦酸酯的合成与生物活性研究  

Studies on Synthesis and Biological Activity for O,O-Dimethyl-2,6-Pyridinyl Diformyloxy Alkyl Phosphonates

作　　者：雷大有[1] 王涛[1] 敖丽华[1] 

机构地区：[1]江西师范大学化学化工学院,江西南昌330022

出　　处：《江西师范大学学报（自然科学版）》2009年第3期267-271,278,共6页Journal of Jiangxi Normal University(Natural Science Edition)

基　　金：江西省自然科学基金(2007GZH1399)资助项目

摘　　要：为了寻找高效低毒的农药,设计、合成了一系列新的2,6-吡啶二甲酰氧基烃基膦酸酯衍生物4a^4i,它们的结构经元素分析,IR,1HNMR and MS测试而确定,初步的生物活性测试结果表明,部分合成的化合物对稗草具有良好的植物生长调节活性.In an attempt to discover novel compounds with high activity and low toxicity, a series of new o ,o-dimethyl-2,6-pyridinyl diformyloxy alkyl phosphonates 4a-4i have been designed and synthesized by the reaction of 2,6- pyridinyl diformyloxy chloride with l-hydroxy-2-alkyl phosphonate. The structures of all new compounds were characterized by elementary analysis, IR,^1H NMR and MS spectroscopies. The results of preliminary bioassay indicate that some of the target compounds have obviously promotive action for plant growth against stalk of barnyard grass.

关 键 词：吡啶 膦酸酯 合成 生物活性 

分 类 号：O625.4[理学—有机化学]