草酸二苄酯的催化合成  

Synthesis of Dibenzyl Oxalate by Catalyst

作　　者：闫涛[1] 张在庆[1] 孙学军[1] 尤进茂[1,2] 

机构地区：[1]曲阜师范大学化学与化工学院山东省生命有机分析重点实验室,山东省曲阜市273165 [2]中国科学院西北高原生物研究所,青海省西宁市810001

出　　处：《曲阜师范大学学报（自然科学版）》2009年第3期61-63,共3页Journal of Qufu Normal University(Natural Science)

基　　金：国家自然科学基金(20075016);山东省自然基金项目(02BS046)

摘　　要：以草酸和苯甲醇为原料,采用三种不同的催化剂对甲苯磺酸、硫酸氢钾、强酸性阳离子交换树脂,三种不同的带水剂甲苯、苯、环己烷,合成了草酸二苄酯.并通过熔点、红外图谱,质谱对产物的结构进行表征.研究了反应物的配比、催化剂的种类和用量、带水剂的种类和用量对产物收率的影响.试验结果表明,当n(草酸)∶n(苯甲醇)=1∶2.2(摩尔比);催化剂为对甲苯磺酸,用量为草酸质量的0.5%(0.13 g);苯为带水剂,用量40 mL,反应时间40 min;反应产率高达96.2%.Taking oxalic acid and benzyl alcohol as raw materials, dibenzyl oxalate was synthesized by using p- toluene sulphonic acid, potassium bisultfute, strong acid ionic exchange resin as catalysts and Toluene, benzene, cyclohexane as water-carrying agents. Structure of the product was identified by means of melting point measurement, IR and LC-MS. By a single factor test, effects of the reactant ratio, variety and quantity of the catalysts and watercarrying agents on the reaction were studied. Results showed the optimal reaction conditions： were n（ oxalic acid）： n（ benzyl alcohol） = 1：2.2 （mole ratio）, p-toluene sulphonic acid 0.15 g, benzene 40 mL, reaction time 40 min,the yield of dibenzyl oxalate reached up to 96.2%.

关 键 词：草酸 苯甲醇 对甲基苯磺酸 草酸二苄酯 

分 类 号：O522.5[理学—高压高温物理]