高血压患者胆红素与血脂综合指数的变化  

The Changes of Bilirubin Level and Composite Index of Serum Lipid in Patients with Essential Hypertension in Xining

作　　者：王明宁[1] 胡琳 

机构地区：[1]青海大学医学院,810001 [2]青海省心脑血管病专科医院,810012

出　　处：《青海医药杂志》2009年第6期5-6,共2页Qinghai Medical Journal

摘　　要：目的:探讨胆红素与血脂综合指数的变化状况对冠心病的诊断价值。方法:对67例高血压组和72例冠脉正常组血清总胆红素(TB)、直接胆红素(DB)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)指标进行测试,分析组间胆红素、血脂、血脂综合指数和胆红素与血脂综合指数的差别。结果:高血压组血清总胆红素明显低于冠脉正常组(P<0.05);高血压组胆红素与血脂综合指数结合指标明显高于冠脉正常组(P<0.01)。结论:胆红素与血脂综合指数是具有临床使用价值的预测指标。Objective：To evaluate the diagnostic effects of composite index variables of the serum bilirubin and serum lipid on coronary disease in predicting essential hypertension （EH）. Methods： Level of Serum total bihrubin （TB）, total cholesterol （ TC ）, triglycerides （TG）, high density lipoprotein cholesterol （ HDL - C）, and low density hpoprotein cholesterol （ IDL - C） were measured in 67 cases of hypertension （EH group ） and 72 normal coronary subjects （Control group ）, and the ratio of TC/ HDL-C, LDL-C/HDL-C, TC/（HDL-C ＋TB） and LDL-C/（HDL-C ＋TB） were recorded. Results： The serums levels of I_DH -L in EH group were increased as compared with that in the control group. （2.85 ±0.95 vs.2.56 ±0. 76, P 〈0.05）. The serum levels of rib in ET group were significantly lower than that in control group. （11.14 ±4. 13 vs. 13.87 ±2.36, P 〈0.05）. The ratio of Tch/（HDL -C ＋TB） and IDL- C/（HDL -C ＋TB） in EH group was significantly higher than that in control group （1.77±0.65vsl.36 ±0.31 ;1.07±0.47 vs.0.71±0.21;P 〈0.01）. Conclusions： The ratio of 3V,/（HDL -C ＋TB） and IDL -C/（HDL-C ＋ TB） is a greater useful value for evaluation of risk of essential hypertension in clinical prediction as corrpared with use of value for single serum lipid only.

关 键 词：胆红素 血脂 血脂综合指数 

分 类 号：R544.1[医药卫生—心血管疾病] R446.11[医药卫生—内科学]