冠心病患者血清NO和hs-CRP水平检测的临床意义  

Clinical singnificance of determination of serum NO and hs-CRP levels in patients with coronary heart diseases

作　　者：秦文敬[1] 

机构地区：[1]江苏省东海县人民医院检验科,222300

出　　处：《淮海医药》2009年第4期295-296,共2页Journal of Huaihai Medicine

摘　　要：目的探讨冠心病患者血清NO和hs-CRP水平的变化及意义。方法应用化学法和免疫比浊法对36例冠心病患者进行血清NO和hs-CRP水平检测,并与35名正常健康人作比较。结果冠心病患者血清NO水平非常显著地低于正常人组(P<0.01),而hs-CRP水平又非常显著地高于正常人组(P<0.01),冠心病患者血清NO水平与hs-CRP水平呈负相关(r=-0.2378,P<0.01)。Objective To explore the significance of serum NO and hs-CRP levels in patients with coronary heart diseases （CHD）. Methods Serum NO （ with chemistry ） and hs-CRP （ with immune tarbility ） levels were determined in 36 patients with coronary heart diseases and 35 controls. Results Serum NO concentration was significantly lower in CHD patients （ P 〈 0. 01 ） ,while the serum hs-CRP concentration was significantly higher in CHD patients（ P 〈0.01 ） ,than those in the controls. Serum NO levels were significantly negatively correlated with those of serum he-CRP（ r = - 0. 2378 ,P 〈 0. 01 ）. Conclusion Combined detection of serum NO and hs-CRP may improve the diagnosis of CHD.

关 键 词：冠状动脉疾病 一氧化氮 超敏C-反应蛋白 

分 类 号：R541.4[医药卫生—心血管疾病]