针灸对照西药治疗膝骨性关节炎的疗效分析  

Meta-analysis for Acupuncture and Moxibustion Treatment of Knee Osteoarthritis

作　　者：柴华[1] 黎波[1] 杜元灏[2] 

机构地区：[1]天津中医药大学,天津300073 [2]天津中医药大学第一附属医院科研处,天津300193

出　　处：《辽宁中医杂志》2009年第7期1197-1200,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家"十一五"科技支撑计划资助项目(2006BAl12B01)

摘　　要：目的:评价针灸治疗膝骨性关节炎的疗效。方法:对针灸治疗膝骨性关节炎的随机对照试验(RCT)进行Meta-分析。统计方法数据使用专用软件RevMan 4.2.8版进行统计分析。结果:6篇RCT共500例患者满足纳入标准。Meta-分析的结果,针刺组和药物组比较,有效率的相对危险度(RR)为2.26,95%的可信区间(1.71,2.99),P<0.00001;总均分的加权均数差值(WMD)为9.83,95%的可信区间(6.21,13.45),P<0.00001。结论:针灸治疗膝骨性关节炎疗效优于西药,且副作用少,具有安全性。但由于临床试验方法学质量不高,尚需要高质量的试验进一步证实。Objective ： To assess the therapeutic effect of acupuncture on knee osteoarthritis. Methods ： A Meta-analysis of all relevant randomized controlled trials（RCT） about acupuncture and moxibustion treatment of knee osteoarthritis was carried out. The data were statistically analyzed with a special software RevMan 4.2. 8. Results ： Six papers of RCT including 500 patients met the enrolled criteria. Meta-analysis indicated that relative risk was 2.26,95% confidence interval（ 1.71,2. 99 ） ,P 〈 0. 00001 ;weighted mean difference was 9. 83,95% confidence interval（ 6. 21,13.45 ） ,P 〈 0. 00001, as acupuncture group compared with drug group. Conclusion ：The therapeutic effect of acupuncture and moxibustion on knee osteoarthritis is superior to that of drug group with safety and less adverse reactions. However, because of lower methodological quality of the trials, this conclusion needs further be confirmed.

关 键 词：膝骨性关节炎 针灸疗法 随机对照试验 META-分析 

分 类 号：R246.2[医药卫生—针灸推拿学]