无创正压通气治疗COPD合并Ⅱ型呼吸衰竭68例疗效观察  

Clinical observation of non-invasive inspirator positive pressure ventilation in the treatment of 68 cases with COPD and coupled with type Ⅱ respiration failure

作　　者：贺明[1] 吴生灵[1] 杨建民[1] 

机构地区：[1]广州新海医院呼吸内科,广东广州510300

出　　处：《中国当代医药》2009年第13期56-58,共3页China Modern Medicine

摘　　要：目的:探讨无创正压通气(NIPPV)治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的疗效。方法:选择2007年2月～2009年2月住院的COPD合并Ⅱ型呼吸衰竭患者68例,并随机分为两组,NIPPV观察组34例,常规对照组34例。观察两组患者治疗前后的血气分析、心率、呼吸频率变化。结果:治疗4h后,NIPPV观察组和常规对照组动脉血氧分压(PaO2)、二氧化碳分压(PaCO2)、呼吸频率均有明显改善,NIPPV观察组明显优于常规对照组(P<0.05)。NIPPV治疗组患者病死率、住院天数较常规对照组明显降低(P<0.05)。结论:NIPPV治疗明显改善COPD合并Ⅱ型呼吸衰竭患者的通气功能、缩短住院天数、降低病死率。Objective：To investigate the non-invasive inspirator positive pressure ventilation （NIPPV） in the treatment of chronic obstructive pulmonary disease （COPD） with type Ⅱ respiratory failure patientsMethod：Selected 68 patients with COPD and coupled with type Ⅱ respiratory failure from February 2007 to February 2009,these patients were randomly divided into two groups,NlPPV group for 34 cases, 34 cases of conventional control group.Observed the blood gas analysis, heart rate, respiratory rate before and after treatment.Results：Be treated after 4 h,NIPPV observed treatment group and eontrol group of conventional arterial partial pressure of oxygen （PaO2）, carbon dioxide partial pressure （PaCO2）, respiratory rate were significantly improved, and observed the NIPPV group was significantly superior to conventional control group（P〈0.05）.NIPPV treatment group mortality, length of hospital stay lower significantly than the conventional control group （P〈0.05）.Conclusion：NIPPV can improve the ventilation of COPD eoupled with type Ⅱ respiratory failure,significantly shorten the length of hospital stay and lower mortality.

关 键 词：无创正压通气 慢性阻塞性肺疾病 呼吸衰竭 

分 类 号：R563.8[医药卫生—呼吸系统]