硬膜外罗哌卡因用于剖腹产术后镇痛的最低运动阻滞浓度  

The minimal local analgesic concentration of epidural ropivacaine for cesarean patients

作　　者：陆智杰[1] 孙雪峰[2] 王晓燕[2] 

机构地区：[1]第二军医大学东方肝胆外科医院麻醉科,上海200438 [2]解放军总医院第一附属医院麻醉科,北京100037

出　　处：《实用临床医药杂志》2009年第5期40-41,共2页Journal of Clinical Medicine in Practice

摘　　要：目的研究剖腹产术后硬膜外镇痛的罗哌卡因最低运动阻滞浓度。方法30例ASAI级的择期剖腹产病人，采用上下序贯法用不同浓度罗哌卡因行硬膜外镇痛，术后12和24h评价镇痛效果和运动阻滞情况。结果罗哌卡因的最低运动阻滞浓度MMLAC为0．301％（95％可信区间0．280％～0．334％）。结论罗哌卡因用于剖腹产术后镇痛的最低运动阻滞浓度为0．301％。Objective To determine the motor block minimal local analgesic concentration （MMLAC） of epidural ropivacaine for cesarean patients. Methods MMLAC, defined as the 50 % effective concentration （ECS0） of femoral articulation blockade, was determined by up-and-down sequential method in 30 patients undergoing selective cesarean. Result MMLAC of epidural ropivacaine estimated in this study was 0. 301% with a 95% confidence interval of 0. 280% to 0. 334 %. Conclusion There is a range of epidural ropivacaine concentraion to produce satisfactory analgesia with little motor block and the result of this study can help to choose a proper ropivacaine concentration for cesarean patients

关 键 词：罗哌卡因 硬膜外镇痛 运动阻滞浓度 

分 类 号：R614.4[医药卫生—麻醉学]