抗菌肽的结构与功能研究  

Research on the Structure and Functions of Antimicrobial Peptides

作　　者：马玻 张玉明[2] 倪志华[2,3] 周艳芬[2,3] 

机构地区：[1]河北大学基础医学院,河北保定071000 [2]河北大学生命科学学院,河北保定071002 [3]河北省生物工程技术研究中心,河北保定071002

出　　处：《安徽农业科学》2009年第23期10878-10880,共3页Journal of Anhui Agricultural Sciences

基　　金：河北省保定市科技局项目(08ZF097)

摘　　要：抗菌肽是一种具有抗菌、抗病毒的天然活性物质。在基础理论研究领域,抗菌肽是研究生物大分子结构的重要材料。同时,其独特的生物抗菌活性又在医药工业具有广阔的应用前景。抗菌肽的结构组成与其生物活性密切相关。以3类典型抗菌肽为例,阐述多肽结构对于生理功能的重要性,以展示抗菌肽重要的理论及应用价值。Antimicrobial peptides are natural bioactive substances with anti-bacterial, anti-viral activity. In the field of fundamental research, antimicrobial peptides are important materials to study the structure of biological macromolecules. At the same time, their unique biological activity will be widely applied in the pharmaceutical industry. Structure of antimicrobial peptides is closely related to their bioactivity. Taking three typical antimicrobial peptides as examples,.the important relation between the structure of peptide and their physiological function was discussed, in order to demonstrate the importance theory and application value of antimicrobial peptides.

关 键 词：抗菌肽 防卫肽 杀菌肽 羊毛硫抗生素 

分 类 号：Q78[生物学—分子生物学]