中药及其成分配伍组方的研究方法探析  

Study of combination methods for formula composition of Chinese herbal medicines and their components

作　　者：刘新军[1] 苏式兵[1] 

机构地区：[1]上海中医药大学复杂系统研究中心,上海201203

出　　处：《中西医结合学报》2009年第7期601-606,共6页Journal of Chinese Integrative Medicine

基　　金：创新方法工作专项(No.2008IM020900);国家科技支撑计划中医药诊疗与评价技术研究项目(No.2006BAI08B02-06);上海市教育委员会E-研究院建设计划资助项目(No.E03008)

摘　　要：中药是依照七情和合、君臣佐使的原则组成方剂的。研究中药方剂配伍组方的方法很多,大致可分为传统模式和现代模式。中药的配伍组方研究已从传统模式发展到现代模式。其中,传统模式又分为全方研究和拆方研究,主要是在饮片层次从整体效果及拆方后药物的配伍组合对复方的作用机制进行剖析;而现代模式的研究主要是中药有效成(组)分的配伍组方研究,是在组分层次上的研究,并能实现药物配伍组方的定量分析。建立新的多成(组)分配伍模式和优化组合研究方法,将有可能使中药配伍组方从饮片层次上升到组分层次,并可能获得成分和作用靶点明确、作用环节及机制清楚的新组方,给中药方剂研究带来突破。Chinese prescription is composed of Chinese herbal medicines according to ＂seven compatible relations＂ and ＂sovereign, minister, assistant and courier＂ principles. There are many methods in the research on combination and composition of Chinese herbal medicines. These methods are classified into traditional model and modern model. For the time being, compatibility study of traditional Chinese herbal medicines has developed from traditional model to modern model. The traditional model mainly studies the effects and mechanisms of the whole and split formulae in medical crude drug level, while the modern model mainly studies the effects and mechanisms of Chinese herbal medicine compositions in components combination level. Moreover, quantitative analysis becomes probable by modern model method. Now, setting up of new components combination model and optimal composition methods will not only develop the combination and the composition of Chinese herbal medicines from medicinal crude drug level to components composition level, but also get new formulae which have clear components and effects, and action targets and mechanisms. It will effectively promote the development of Chinese medicine formula.

关 键 词：中药 配伍 规律 

分 类 号：R289[医药卫生—方剂学]