羟乙基淀粉对梗阻性黄疸病人术后血浆清蛋白和免疫功能的影响  

Effects of treatment with hydroxythy starch on the serum albumin and immunologic function in postoperative patients with obstructive jaundice

作　　者：代安银[1] 徐鹏远[1] 孙大力[1] 岑云云[1] 陈雄志[1] 刘剑[1] 李为明[1] 戚宇星[1] 

机构地区：[1]昆明医学院第二附属医院干疗外科,云南昆明650101

出　　处：《肠外与肠内营养》2009年第4期215-218,共4页Parenteral & Enteral Nutrition

摘　　要：目的:观察梗阻性黄疸病人术后应用羟乙基淀粉(130/0.4)对血浆清蛋白和免疫功能的影响。方法:将24例梗阻性黄疸病人随机分为对照组和试验组,每组各12例。试验组病人自术后即开始输注羟乙基淀粉(130/0.4)10 mL/(kg.d),至术后第7天;对照组病人输注同等量等渗盐水。并于术后第1、3、5和7天测定血浆ALB含量,于术后第1和第7天检测免疫指标。结果:两组病人术后第1和第7天血浆ALB含量比较无显著差异(P>0.05),而术后第3和第5天血浆ALB含量有显著性差异(P<0.05)。两组病人免疫指标无显著性差异(P>0.05)。结论:梗阻性黄疸病人术后使用羟乙基淀粉(130/0.4)可减轻ALB含量的下降,而对病人免疫功能则无明显影响。Objective ： To investigate the effects of trentment with hydroxythy starch （130/0.4） on the serum albumin and immunologic function in postoperative patients with obstructive jaundice. Methods： 24 patients with obstructive jaundice were randomly divided into the control group （n = 12 ） and hydroxythy starch（130/0.4） （HS） group（n = 12）. The serum ALB was detected ld, 3d, 5d, 7d after the operation, and the immunologic index were detected 1 d and 7d after the operation. Results： The ALB content of control group and HS group were not significantly different in the postoperative 1 d and 7 d （P 〉 0.05） and had significant differences in the postoperative 3 d, 5 d （P 〈 0.05 ）. All immunologic index had no significant differences in the postoperative 1 d, 7d （P 〉 0.05 ）. Conclusion： The ALB content of patients with obstructive jaundice may decrease postoperatively. Treatment with hydroxyhhy starch（130/0.4） can alleviate the drop of the ALB content. But it has no effects on immunologic function.

关 键 词：羟乙基淀粉 免疫功能 梗阻性黄疸 清蛋白 

分 类 号：R657.4[医药卫生—外科学]