静脉注射咪达唑仑与芬太尼用于ICU机械通气患者镇静的临床观察  

Sedative effect of midazolam and fentanyl on ventilated patients in ICU

作　　者：赵广阔[1] 张芝晶[1] 

机构地区：[1]大连市中心医院急诊病房,辽宁大连116033

出　　处：《现代医药卫生》2009年第15期2275-2276,共2页Journal of Modern Medicine & Health

摘　　要：目的:观察咪达唑仑与芬太尼联合用药对于机械通气患者的镇静效果。方法:对30例ICU机械通气患者给予咪达唑仑和芬太尼联合镇静,维持理想的镇静深度3～4级,观察各项镇静指标。结果:镇静效率(87±8.8)%,咪达唑仑镇静满意期间的平均输注速度为(0.14±0.02)mg·kg-1·h-1。镇静期间血压、心率平稳。停药后完全清醒时间为(90±24.8)min,拔除气管插管时间(140±36.6)min。拔管后1h血气正常。结论:咪达唑仑与芬太尼联合用于ICU机械通气患者可获得满意的镇静效果。Objective：To observe the sedative effect of midazolam and fentanyl on the patients with mechanical ventilation in ICU. Methods：Midazolam and fentanyl were given by continuous infusion following a load dose to provide satisfactory sedation in 30 patients requiring mechanical ventilation. Results：The sedation efficiency was （87±8.8）%.The average infusion rate of midazolam during the sedative period was （0.14±0.02）mg .kg^-1 .h^-1, while the heart rates and blood pressures remained stable. The time for recovery of consciousness was （90±24.8）min and the time to extubation was （140±36.6）min. The blood gas analysis was normal in 1 h after extubation. Condusion：Midazolam and fentanyl can provide satisfactory sedation for ICU patients.

关 键 词：镇静 机械通气 咪达唑仑 芬太尼 

分 类 号：R5[医药卫生—内科学]