ApoB100和ApoB/10A0poA1比值是预测急性冠脉综合征的良好指标  

ApoB100 and ApoB100/ApoA1 ratio are better predictors of acute coronary syndrome

作　　者：陈文思[1] 黄骥斌[2] 李朝霞[1] 

机构地区：[1]中山大学附属第三医院检验科,广州510630 [2]四川大学华西医院实验医学科,成都610041

出　　处：《中国卫生检验杂志》2009年第7期1571-1573,共3页Chinese Journal of Health Laboratory Technology

基　　金：中山大学附属第三医院院基金(A967)

摘　　要：目的:评价载脂蛋白(apolipoprotein,apo)A1、apoB100及其比值预测急性冠脉综合征(acute coronary syndrome,ACS)发生的临床价值。方法:采用回顾性病例-对照研究,分析比较病例组患者发病前和对照组一年前测定的apoA1、apoB100及apoB100/apoA1比值,并计算其优势比(odds ratio,OR)。结果:ACS病例组患者发病前apoB100和apoB100/apoA1比值显著高于对照组(P<0.05),其OR值分别为12.73和20.34。而apoA1与对照组比较无明显差异(P>0.05),OR值为1.84。结论:apoB100和apoB100/apoA1比值对预测ACS发生有重要意义。Objective： To investigate whether apoA1, apoBlO0 and apoBl00/apoA1 ratio can predict ACS efficiendy. Methods：ACS patient group and control were chosen. The records of apoA1, apoBl00 and apoB100/apoA1 ratio before ACS coming on were taken down and analyzed by statistical methods. Results： ApoB100 and apoB100/apoA1 ratio were increased significantly（ P 〈 0. 05 ）in the patient group compared with the control, so were the odds ratios （OR values）, though the apoA1 was not. Conclusion：The apoB100 and apoBl00/apoA1 ratio are valuable for predicting ACS.

关 键 词：载脂蛋白 急性冠脉综合征 心血管危险因素 

分 类 号：R446.1[医药卫生—诊断学]