腹泻弧菌530株分布及耐药特点分析  

Distribution and antimicrobial resistance of 530 Strains of Vibrio associated from diarrhea patients

作　　者：冯艳青[1] 刘振红[1] 张菊玲[1] 陈素明[1] 郭桐生[1] 崔恩博[1] 鲍春梅[1] 曲芬[1] 毛远丽[1] 

机构地区：[1]解放军302医院临床检验中心,北京100039

出　　处：《中国卫生检验杂志》2009年第7期1604-1606,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的：探讨我院2000-2007年与腹泻有关的弧菌的分布及耐药特点,为有效防治提供依据。方法：通过动力试验、大便培养,筛出致病菌后经生化及血清学进一步鉴定到种,并以纸片扩散法测定了抗菌药物的敏感性。结果：8年分离到弧菌530株9个种,分布以男性为主,青壮年比例较高,7-8月为弧菌感染高峰。弧菌以副溶血弧菌居首位占82%,有增多趋势。弧菌对AMP,PIP,CTX,CRO,FEP,CMZ,LEV,C IP,OFX,NFX,SMZ,CHL,FOS的敏感率分别为18.8%,88.3%,94.9%,96.1%,97.4%,95.5%,96.7%,94.3%,95.6%,95.8%,86.1%,93.8%和97.3%。住院患者的耐药率大多高于门诊患者。结论：北京地区致腹泻弧菌分布和耐药性有其自身特点,应根据监测结果针对性地防治。Objective：To monitor the distribution and antimicrobial resistance of Vibrio isolated from diarrheal patients in our hospital form 2000 to 2007 to offer the evidence of prevention and treatment effectively. Methods：The pathogenic Vibrio was bolted by motility and culture and identified to species by biochemical and serologic test. Then the susceptibility of Vibrio to antimierobial agents was tested. Results：530 Vibrio isolates containing 9 species during 8 years distributed in male youth mainly. It reached peak in June to AugusL Vibrio parahaemolyticus （ 82% ） was the most frequently pathogens and had tendency of increase. The sensitive rate of Vibrio to AMP, PIP, CTX, CRO, FEP, CMZ, LEV, CIP, OFX, NFX, SMZ, CHL, FOS was 18. 8%, 88.3%, 94.9%, 96.1%, 97.4%, 95.5%, 96.7%, 94.3%, 95.6%, 95.8%, 86.1%, 93.8% and 97.3% respectively. Moreover, the resistant rate of Vibrio to most of antibiotics in inpatients was higher than that of outpatients. Conclusion ：The distribution and antimicrobial resistance of Vibrio have it＇s feature in Beijing. So we should take prevention and treatment according to the monitoring results.

关 键 词：弧菌 腹泻 分布 耐药性 

分 类 号：R378[医药卫生—病原生物学]