咽异感症合并焦虑和抑郁患者的治疗  

Treatment of Anxious and Depressive Disorders in Patients with Globus Pharyngeus

作　　者：周剑勇[1] 严飞鹏[1] 常明章[1] 吕洁瑜[1] 熊国平[1] 章晓军[1] 

机构地区：[1]江门市中心医院耳鼻咽喉科,广东江门529071

出　　处：《实用临床医学（江西）》2009年第6期82-84,87,共4页Practical Clinical Medicine

基　　金：江门市科技攻关计划项目(00G030-02)

摘　　要：目的探讨咽异感症患者焦虑和抑郁症状的治疗效果。方法用汉密顿焦虑量表(HAMA)和抑郁量表(HAMD)前瞻性评估109例咽异感症患者,分为对照组(30例)和观察组(79例)。对照组采用常规治疗,观察组在常规疗法的基础上,给予抗焦虑和抑郁治疗即盐酸帕罗西汀、苯二氮卓类药物治疗。结果治疗8周后随访,对照组有效率为50.0%(15/30),观察组为87.3%(69/79),统计学分析表明2组之间差异有显著性(P<0.005)。观察组抗焦虑和抑郁治疗后HAMA和HAMD积分较治疗前明显减少(P<0.01)。结论焦虑和抑郁症状在咽异感症患者中极为常见,抗焦虑抑郁治疗效果确切,可以作为咽异感症的治疗选择。Objective To investigate therapeutic effect of anxious and depressive disorders in patients with globus pharyngeus. Methods 109 patients with globus pharyngeus were assessed prospectively with Hamilton anxiety scale （HAMA） and Hamilton depression scale （HAMD）, and were divided into control group（30） and observed group（79）. The routine method was employed to the control group patients. Antianxiety agents and antidepressants such as paroxetine hydrochloride,benzodiazepines were added to the observed group patients. Results 15 （50. 0%） patients recovered in the control group,and 69（87.3%） in the observed group after 8 weeks treatment. Statistical analysis showed that there were significant difference of therapeutic effects between 2 groups（P〈0.005）. The scores of HAMA and HAMD in the observed group after treatment of antianxiety agents and antidepressants were much less than that before treatment （P〈 0.01）. Conclusion There is a high prevalence of anxious and depressive disorders in patients with globus pharyngeus to be found at present study. The treatments of globus pharyngeus with antianxiety agents and antidepressants are apparent effective in the study, and may be considered as one of the alternative methods.

关 键 词：焦虑障碍 抑郁障碍 咽疾病 

分 类 号：R766[医药卫生—耳鼻咽喉科]