黄芪浸出液对致龋菌的体外抑菌实验  

In vitro antibiotic effect of the leaching solution of astragalus on cariogenic bacteria

作　　者：张金婷[1] 邓旎[1] 车团结[2] 康妍丽[3] 何祥一[1] 

机构地区：[1]兰州大学口腔医学院,730000 [2]兰州大学生命科学院细胞生物学研究所 [3]兰州大学天浩医院口腔科

出　　处：《实用口腔医学杂志》2009年第4期588-590,共3页Journal of Practical Stomatology

基　　金：兰州大学交叉学科青年创新研究基金项目(编号:20071218)

摘　　要：选择甘肃产黄芪为原料,制成水浸出液,研究其对口腔常见致龋菌的抑制效果,并与国外致龋菌抑菌产品(MI)进行比较。以变形链球菌、乳酸杆菌为实验菌株,用选择性培养基进行液体培养,在培养基中添加不等量的药物,测培养24h后菌液的A值、pH值;用SPSS13.0对数据进行统计分析。黄芪浸出液对变形链球菌、乳酸杆菌的生长、产酸均有抑制效果,抗菌效果与MI相当。Astragalus produced in Gansu were chosen as the raw material to leaehate. Studied the antibiotic effects of the leaching solution on the cariogenic bacteria and compared with the imported bacteriostatic product MI. Streptococcus mutans and LactobaciIli were cultured in the medium for 24 h. The Pit/and A600 values were measured. Statistical analysis was conducted by using SPSS 13.0. The leaching solution of astragalus has the same inhibitory effects on the growth and acid production of streptococcus mutans and lactobacilli as MI.

关 键 词：黄芪 变形链球菌 乳酸杆菌 产酸 

分 类 号：R285[医药卫生—中药学]