代谢综合征与前列腺体积的相关性  

Correlation study of metabolic syndrome and prostate volume

作　　者：崔师玉[1] 李茵茵[1] 林海燕[1] 车筱琪[1] 王哲[1] 陈海燕[1] 

机构地区：[1]山东大学附属省立医院保健科,济南250021

出　　处：《中华老年医学杂志》2009年第7期549-551,共3页Chinese Journal of Geriatrics

摘　　要：目的探讨代谢综合征（metabolic syndrome，MS）与前列腺体积的相关性。方法选择年龄36～90岁男性1098人，采用2004年中华医学会糖尿病学分会提出的MS建议诊断标准，分为MS组和对照组。测量血压、身高、体质量，计算体质指数（BMI）。生化分析包括血糖、总胆固醇、三酰甘油、低密度脂蛋白胆固醇（LDL—C）、高密度脂蛋白胆固醇（HDL—C）和前列腺特异性抗原（PSA）。采用经腹部超声测量前列腺体积。结果（1）与对照组比较，MS组的BMI、收缩压、舒张压、空腹血糖、三酰甘油、总胆固醇、前列腺体积和PSA水平较高，但HDL-C水平较低（均P〈0．05）；（2）MS组前列腺体积较对照组增大，分别为（31.0±11．1）ml和（37．8±21．3）ml，两组差异有统计学意义（P〈0．01）；（3）前列腺体积与血清PSA水平（r=0．350，P〈0．01）、年龄（r=0．429，P〈0．01）、BMI（r=0．145，P〈0．01）、收缩压（r=0．133，P〈0．05）呈正相关，与舒张压（r=-0．193，P〈0．01）呈负相关。结论MS与前列腺体积增大有关。Objective To explore the relationship between metabolic syndrome （MS） and prostate volume. Methods One thousand and ninety-eight males aged 36-90 years were divided into two groups according to the definition of MS by CDS in 2004 ： MS group and control group. The blood pressure, body weight and height were measured, and the body mass index （BMI） was calculated. Biochemical assays including fasting plasma glucose, total cholesterol, triglycerides, low density lipoprotein cholesterol （LDL-C）, high density lipoprotein cholesterol （HDL-C）, and prostate specific antigen （PSA） were performed. Prostate volume was measured by abdominal ultrasound. Results （1） The BMI, systolic blood pressure, diastolic blood pressure, fasting plasma glucose, serum triglyeeride, total cholesterol, prostate volume and PSA level were higher, while HDL-C level was lower in MS group than in control group （all P〈0.05）. （2） Compared with control group, the prostate volume was enlarged in MS group [（37.8±21.3）ml vs. （31.0±11. 1）ml, P〈0. 01]. （3）The prostate volume was positively correlated with PSA level （r=0. 350,P〈0.01）,age（r=0. 429,P〈 0.01）, BMI （r=0.145,P〈0.01） and systolic blood pressure （r=0.133, P〈0.05）, and was negatively correlated with diastolic blood pressure （r=-0. 193,P〈0. 01）. Conclusions Metabolic syndrome is related to the enlargement of prostate volume.

关 键 词：前列腺增生 前列腺特异抗原 代谢综合征X 

分 类 号：R686[医药卫生—骨科学]