儿童川崎病56例临床探讨  

Clinical analysis of 56 cases on kawasaki diseas

作　　者：张松青[1] 牛静[1] 张晓静[1] 商梅[1] 

机构地区：[1]济南市妇幼保健院儿科,济南250001

出　　处：《中国医疗前沿》2009年第13期67-69,共3页China Healthcare Innovation

摘　　要：目的探讨川崎病的临床特点。方法对2001年6月至2009年1月住院治疗的56例川崎病病例进行回顾性分析。结果符合川崎病诊断标准的6项主要表现者28例(50%);符合5项主要表现者21例(37.5%);符合4项表现者6例(10.7%);有1例(1.8%)患儿病程中仅有发热,而无川崎病其它主要临床表现;合并冠状动脉病变27例(64.3%)。治愈:本组患者治愈48例,好转7例,自动出院1例,无死亡病例。除自动出院者外,所有病例均随访3个月至3年,冠脉扩张<4mm者均在3个月内恢复正常,4～7mm者约在6个月恢复正常,其中1例冠脉扩张9mm者仍在随访中。结论大多数川崎病患者症状较典型,可明确诊断,大剂量丙种球蛋白治疗效果较好。不完全性川崎病冠状动脉病变发生率高,临床应重视早期诊断和早期治疗。Objective TO study the occurrence and characteristic of Kawasaki disease in children. Methods The data of 56 cases with Kawasaki disease in children from June 2001 to January 2009 were retrospectively analyzed. Results According to the diagnosis criteria of Kawasaki disease,28 children met to 6 main symptoms which counted for 50%,21 children met to 5 main symptoms which counted for 37.5%,6 children met to 4 main symptoms which counted for 10.7%.I children which counted for 1.8% only had fevers during the course of the disease and without any other clinical manifestation. 27 children which counted for 64.3% had the complication of coronary artery lesions.After treatment,48 children were cured,7 improved,1 gave up and no one died.Except for the one that gave up treatment ,all children received follow-up in the next 3 months to 3 years.Diameter of coronary artery dilatation （〈4ram）could return to normal in 3 months,while those diameters of comary artery dilatation that were between 4-7mm could return to normal in 6 months.One children that diameter of cornary artery dialation was 9mm was still receiving the follow- up. Conclusion Most of the children with Kawasaki disease have typical symptoms and could be diagnozed correctly.high dosage WIG could have a good therapeutic efficacy.The rate of coronary artery lesions is higher in incomplete Kawasaki disease,and it should be paid more attention to earlier diagnosis and earlier treatment.

关 键 词：川崎病 不完全性川崎病 丙种球蛋白 

分 类 号：R725.4[医药卫生—儿科]