不同空腹血糖水平血清白介素18与白介素6含量及相关因素分析  

The serum interleukin-18 and interleukin-6 concentration and their associated factors under different fasting plasma glucose

作　　者：谢晓敏[1] 牛旭东[1] 李仁达[1] 于丽萍[1] 周海燕[1] 张丽[1] 刘惠莉[1] 李玲[1] 曾斌[1] 史静[1] 

机构地区：[1]宁夏医学院第二附属医院银川市第一人民医院内分泌科,750001

出　　处：《中国糖尿病杂志》2009年第7期539-540,共2页Chinese Journal of Diabetes

基　　金：宁夏银川市科技攻关基金资助项目(06-1-60)

摘　　要：分析不同FPG状态下血清白介素18(IL-18)、IL-6含量及相关因素,发现不同FPG水平下血清IL-18水平有明显不同(P<0.01),且随FPG升高而升高;血清IL-6水平在FPG≥6.1mmol/L时显著增高(P<0.01,P<0.05)。推测IL-18可能是导致2型糖尿病发生的重要细胞因子之一。We analyzed the relationship of FPG with the concentration of IL-18 and IL-6 in the situation of different fasting plasma glucose. The serum IL-18 levels were significantly different among all groups（P〈0. 01）. With FPG increasing, the IL-18 levels were increased. The serum IL-6 levels were higher in the subjects with FPG≥6. lmmol/L （P〈0. 05）. IL-18 might be an important molecule for advancing type 2 diabetes.

关 键 词：空腹血糖 白介素18 白介素6 

分 类 号：R587.1[医药卫生—内分泌]