α-(2,4-二氯苯氧基乙酰氧基)-α-芳甲基膦酸酯的合成、晶体结构及除草活性  

Synthesis,Crystal Structure and Herbicidal Activity of α-(2,4-Dichlorophenoxyacetoxy)-α-arylmethylphosphonates

作　　者：王涛[1] 贺红武[2] 缪方明[3] 

机构地区：[1]江西师范大学化学化工学院,南昌330022 [2]华中师范大学化学学院有机合成研究所,武汉430079 [3]天津师范大学晶体化学研究所,天津300073

出　　处：《有机化学》2009年第7期1152-1157,共6页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.20372023;20862007);国家十五重点科技攻关资助项目

摘　　要：通过2,4-二氯苯氧基乙酰氯和α-羟基芳甲基膦酸酯的缩合反应合成了12种标题化合物,用元素分析,IR,1HNMR及MS作了表征.为进一步了解此类化合物的结构,用X射线单晶衍射测定了化合物4a的晶体结构.初步的生物活性测试表明,部分化合物对单、双子叶植物根的生长具有优异的抑制作用.质量浓度分别为100和10mg/L时,化合物4a～4l对油菜根和稗草根的生长抑制率均超过90%。Twelve novel α-（2,4-dichlorophenoxyacetoxy）arylmethylphosphonates were synthesized from the intermediate （α-hydroxyl）-α-arylmethylphosphonates and 2,4-dichlorophenoxyacetyl chloride. All compounds synthesized were identified by ^1H NMR,IR and MS techniques. The crystal structure of the compound 4a was determined by X-ray single-crystal diffraction. Preliminary bioassay results showed that some of these compounds had better inhibiting effect against the roots of rape and barnyard grass. Inhibitory rates of compounds 4a-41 against the roots of rape and barnyard grass were more than 90% at a dosage of 100 and 10 mg/L respectively.

关 键 词：芳烷基膦酸酯 合成 生物活性 晶体结构 

分 类 号：TQ450.2[化学工程—农药化工]