半仿生法提取白附子的工艺研究  

Optimization of Semi-bionic Extraction of Rhizoma Typhonii

作　　者：曹志友[1] 王新城[1] 欧阳瑾[1] 雷钧涛[2] 

机构地区：[1]吉林医药学院直属医院,吉林吉林112013 [2]吉林医药学院.药学院,吉林吉林132013

出　　处：《时珍国医国药》2009年第7期1691-1692,共2页Lishizhen Medicine and Materia Medica Research

基　　金：吉林省教育厅重点资助项目(No.吉教科合字[2007]第242号)

摘　　要：目的优化白附子最佳提取工艺。方法以β-谷甾醇得率为指标,在提取次数、提取工艺、浸渍剂浓度等条件相同时,考虑乙醇溶液pH值、提取时间、提取温度,选用L16(45)正交进行实验,确定最佳提取工艺。结果最佳提取工艺为第1煎提取液pH为7,第2煎提取液pH为9,提取温度85℃,提取时间6h。结论半仿生提取法优选白附子最佳提取工艺,方法简便,可行。Objective To optimize the semi - bionic extraction of Rhizoma Typhonii. Methods Under the unchanged conditions including extracting frequency, extracting course and concentration of solvent , with the yield rate of isoflavonoids of Rhizoma Typhonii as index as index, L16 （4^5 ） orthogonal design was used to investigate the effects of pH, extraction temperature, and extraction time. Results The first extraction pH was 7. The second extraction pH was 9. The extraction temperature was 85 ℃. The extraction time was 6 hours. Conclusion Optimization of semibionic extraction methods of Rhizoma Typhonii by orthogonal design is available.

关 键 词：白附子 半仿生提取法 Β-谷甾醇 正交设计 

分 类 号：R284.2[医药卫生—中药学]