柴茯调脂口服液对高血脂大鼠模型的影响  

Effect of Chaifu Tiaozhi Oral Liquid on Hyperlipaemia Rats

作　　者：宋卫国[1] 

机构地区：[1]山东省中医药研究院,山东济南250014

出　　处：《时珍国医国药》2009年第7期1755-1756,共2页Lishizhen Medicine and Materia Medica Research

摘　　要：目的实验观察柴茯调脂口服液对高血脂模型大鼠的影响,为临床用药提供药效学依据。方法给予大鼠高脂饲料20d,造成高血脂大鼠模型,测定灌服柴茯调脂口服液后高脂模型大鼠甘油三酯(TG)、胆固醇(CHOL)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、超氧化物歧化酶(SOD)、丙二醛(MDA)等指标的变化。结果柴茯调脂口服液高剂量明显降低大鼠血清TG,CHOL,LDL,MDA含量,提高HDL含量和SOD活性。结论柴茯调脂口服液具有明确的调节高血脂症的作用。Objective To study the effect of Chaifu Tiaozhi Oral liquid on hyperlipademia rats. Methods The model of hyperlipidemia in rats was established by abundant fat feeding for 20 days. The contents of TG, CHOL, LDL, HDL, SOD, MDA were determined after given Chaifu Tiaozhi Oral liquid by oral garage. Results Chaifu Tiaozhi Oral liquid could reduce the con^ents of TG, CHOL, LDL, MDA in rat serum obviously, improve content of HDL, increase the activity of SOD. Conclusion Chaifu Tiaozhi Oral liquid has regulative effect on hyperlipidemia.

关 键 词：柴茯调脂口服液 高血脂模型 大鼠 

分 类 号：R285.5[医药卫生—中药学]