卵巢颗粒细胞凋亡的调控因素  

The Regulating Factors of Apoptosis of Ovary Granular Cells

作　　者：刘鹏[1] 李向臣[1] 姚雅馨[2] 乔利敏[2] 关伟军[1] 马月辉[1] 

机构地区：[1]中国农业科学院北京畜牧兽医研究所,北京100193 [2]甘肃农业大学动物医学院,甘肃兰州730070

出　　处：《现代生物医学进展》2009年第13期2562-2564,共3页Progress in Modern Biomedicine

基　　金：国家自然科技资源平台建设项目(2005DKA21101)

摘　　要：卵泡闭锁是哺乳动物卵巢中一种普遍现象,其实质是由卵巢颗粒细胞凋亡造成的。颗粒细胞的状态已经成为衡量卵母细胞质量乃至胚胎发育能力的一个重要参考指标,因此对颗粒细胞的凋亡开展研究显得十分必要。调控颗粒细胞凋亡的因素有多种,本文从与颗粒细胞凋亡相关的激素、与颗粒细胞凋亡相关细胞因子和与颗粒细胞凋亡相关的基因三方面对卵巢颗粒细胞凋亡的调控因素进行综述。Follicular atersia is a common phenomenon in mammal ovary. In fact it is caused by apoptosis of ovary granulose cells. The status of granulose cells has already became an important index of evaluating the quality of oocytes and developmental ability of embryos, so it＇s necessary to deliver research on apoptosis of ovary granulose cells. There are many factors controlling the apoptosis of granulose cells. In this article, we discussed three main factors relating to apoptosis of granulose cells that are reproductive hormone, cytokine and controlling genes of apoptosis.

关 键 词：颗粒细胞 凋亡 调控因素 

分 类 号：Q78[生物学—分子生物学] Q255