滋阴通淋方对慢性尿路感染患者IL-6的影响  

Influence of "Ziyin Tonglin Decoction" on IL-6 in Patients with Chronic Urinary Tract Infection

作　　者：冯继伟[1] 高继宁 

机构地区：[1]上海市浦东新区公利医院肾内科,上海200135 [2]山西省中西医结合医院肾内科,山西太原030012

出　　处：《上海中医药杂志》2009年第7期39-40,共2页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市浦东新区社会发展局课题(PW2002-13)

摘　　要：目的观察滋阴通淋方治疗慢性尿路感染的临床疗效及其对患者机体免疫功能的影响。方法将60例患者随机分为治疗组和对照组(各30例);治疗组服用滋阴通淋方,对照组服用左氧氟沙星片;两组疗程均为4周,疗程结束后,观察临床疗效及外周血、尿中白细胞介素-6(IL-6)的变化情况。结果治疗组、对照组总有效率分别为86.6%和63.3%;组间疗效比较,差异有统计学意义(P<0.05)。治疗组治疗后主要症状积分明显降低(P<0.05);组间治疗后比较有显著差异(P<0.05)。治疗组治疗前后外周血、尿中IL-6均明显降低(P<0.05);组间治疗后比较,外周血、尿IL-6差异均有统计学意义(P<0.05)。结论滋阴通淋方对慢性尿路感染有良好的效果,具有免疫调节和抗炎的双重作用。Objective To observe the clinical efficacy of ＂Ziyin Tonglin Decoction＂ in the treatment of chronic urinary tract infection and its influence on immune function. Methods Sixty subjects were randomly divided into two groups： treatment group in which 30 eases were given ＂Ziyin Tonglin Decoction＂ and control group in which another 30 cases were given levofloxacin tablets, with a course of 4 weeks. The clinical efficacy and the levels of blood and urine IL-6 were observed. Resuits The total effective rate was 86.6% in treatment group and 63.3% in control group（ P 〈0.05 ） ; after treatment, the symptom score and the levels of blood and urine IL -6 were reduced evidently（ P 〈0.05 ） , with great differences in comparison with control group（ P 〈0.05 ）. Conclusion ＂Ziyin Tonglin Decoction＂ is quite effective for chronic urinary tract infection, and has dual action in regulating immunity and fighting inflammation.

关 键 词：慢性尿路感染 中医药疗法 滋阴通淋方 白细胞介素-6 

分 类 号：R277.5[医药卫生—中医学]