丹参对全胃肠外营养致肝损伤的防治疗效观察  

To observe the therapeutic effect of Danshen Root in preventing and curing hepatic injury by total parenteral nutrition

作　　者：钟小兰[1] 廖小明[1] 彭伯坚[1] 徐志均[1] 

机构地区：[1]广州市花都区人民医院,510800

出　　处：《中国医学创新》2009年第20期65-66,共2页Medical Innovation of China

基　　金：广州市卫生局资助项目(No.2007A34)

摘　　要：目的通过临床病例观察和分析,探讨注射用丹参在全胃肠外营养(total parenteral nutrition;TPN)治疗中肝损伤的疗效。方法将2007～2008年临床收集的各种需要短期TPN治疗的住院病例24例,随机分为对照组和治疗组,两组均予TPN治疗,治疗组加用注射用丹参静脉滴注,检测病例肝功能的变化。结果对照组7例伴有肝损伤,其中2例伴中度ALT升高;治疗组4例伴有轻度肝损;相对治疗组,对照组ALT明显升高,具有明显的差异。短期TPN引起的肝损伤以ALT和ALP的升高为主。结论丹参对TPN引起的肝损伤具有一定的防治作用。Objective To observe the therapeutic effect of Danshen Root in preventing and curing hepatic injury by total parenteral nutrition （TPN） , through the analysis of clinical ＇ease. Methods Have collected 24 clinical eases which need short - term treatment of TPN and separated them with control group and treat group, both groups were treated by TPN, but the treat group were gave extra - treatment by Danshen Root injection, then to get and analysis the messages of hepatic function about two groups. Results There were 7 eases with hepatic injury coneomitaney in control group, but 4 eases in treat group, all of them have higher ALT and ALP than normal ; the ALT were much higher in eontrol eases than treat eases. Conclusion From the results we know that Danshen Root can prevent and cure the hepatic injury by TPN.

关 键 词：全胃肠外营养 肝损伤 丹参 

分 类 号：R459.3[医药卫生—治疗学]