用于荧光免疫光纤生物传感器中信号分析的理论模型  

Theoretical Model Used for the Analysis of the Signal of Fluorimmunoassays Fiber-Optic Biosensor

作　　者：王京生[1] 冯莹[1] 陈爽[1] 魏立安[1] 柳珑[1] 

机构地区：[1]国防科技大学光电科学与工程学院,长沙410073

出　　处：《光子学报》2009年第7期1647-1650,共4页Acta Photonica Sinica

基　　金：国防科技大学基础研究资助

摘　　要：利用多层介质中偶极子辐射理论,得到了荧光免疫光纤生物传感器的初始荧光分布.在此基础上,利用几何光波导理论给出了荧光信号在光纤探针中的传输模型.通过定义光纤探针的耦合效率、传输效率、收集效率和有效收集效率等概念,实现了对基于倏逝波激发的荧光免疫光纤生物传感器系统中荧光信号的跟踪分析.并建立了理论模型,可用于该类传感器系统的优化设计.Using the theory of radiation of dipoles placed within a multilayer system, the original distribution of fluorescence of flour-immunoassays fiber optic biosensor is presented. The transmission model of fluorescence signal is achieved by using the classical geometric optical waveguide theory. After introducing the Coupling Efficiency,the Transporting Efficiency,the Collecting Efficiency and the Effective Collecting Efficiency,the analysis of fluorescence signal of the fiber-optic biosensor based on evanescent wave is realized. The model is helpful to optimization of the system of such kind.

关 键 词：光纤生物传感器 荧光信号分析模型 偶极子辐射 几何光波导理论 效率 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置]