呼和浩特地区5014例献血人群不规则抗体筛查分析  

Screening Analysis of Irregular Antibodies of 5014 Blood Donors in Hohhot Area

作　　者：张伟[1] 张俊玲[1] 尚锦清[1] 白俊凤[1] 

机构地区：[1]内蒙古自治区血液中心,呼和浩特市010070

出　　处：《职业与健康》2009年第16期1735-1737,共3页Occupation and Health

摘　　要：目的分析呼和浩特地区不规则抗体的频率与分布特征,以确保输血安全。方法于2008年对呼和浩特地区献血者中随机抽取5014例,采用抗体筛选细胞、聚凝胺试验和抗人球蛋白试验作抗体筛查。结果筛出不规则抗体9例,占0.18%。女性不规则抗体者多于男性(P<0.01),多为Rh抗体(抗D、抗E和抗C占55.6%)。聚凝胺法漏检1例Le抗体。结论由于不规则抗体可以导致溶血性输血反应和新生儿溶血病,因此调查该地区不规则抗体对安全输血十分重要。对女性献血者或给重危病人、小儿大量输注的血浆尤应做抗体筛选以确保安全输血。[ Objective] To analyze the frequency and distribution of irregular antibodies in Hohhot area so as to ensure the safety of blood transfusion. [ Methods] Blood donors of Hohhot area were randomly selected in 2008; antibody screening cells, polybrene test and anti-human globulin test were adopted for antibody screening. [ Results ] The irregular antibodies were found in 9 samples （0.18% ）. The frequency of irregular antibodies in female was higher than that in male（ P 〈0.01 ） and Rh antibodies such as anti- D, anti-E, and anti-Ec C （ 55.6% ） were common. One sample of Le antibodies was failed to be found by polybrene test. [ Conclusion ] Because of irregular antibodies resulting in hemolytic transfusion reaction, the investigation of irregular antibodies is very important for ensuring blood transfusion. Antibody screening must be done for massive plasma transfusion of female donors, severe patients and infants to ensure safety.

关 键 词：不规则抗体 抗体筛查 

分 类 号：R181.3[医药卫生—流行病学]