胎儿纤维连接蛋白与支原体宫颈炎和羊水胎粪污染关系的研究  

Study on the relationship between the fetal fibronectin and mycoplasma cervicitis or meconium pollution

作　　者：王蕾[1] 夏文艳[1] 黄丽梅[1] 

机构地区：[1]深圳市龙岗区人民医院,广东深圳518172

出　　处：《中国优生与遗传杂志》2009年第8期44-45,共2页Chinese Journal of Birth Health & Heredity

基　　金：广东省科技厅社会发展计划(编号:53077);广东省深圳市龙岗区科技计划医疗卫生项目资助计划(编号:YL-2007044)

摘　　要：目的通过检测胎儿纤维连接蛋白(FFN),研究支原体宫颈炎和羊水胎粪污染的关系,为预测胎儿窘迫提供新方法。方法采用酶联免疫吸附法(ELISA)对支原体宫颈炎患者120例(研究组),健康孕妇81例(对照组)进行宫颈阴道分泌物FFN检测,以FFN≥50ng/mL为判断阳性标准。结果研究组FFN阳性患者75例,阳性率62.5%(75/120),对照组FFN阳性患者31例,阳性率38.2%(31/81);研究组羊水胎粪污染18例,阳性率24%(18/75),对照组羊水胎粪污染2例,阳性率4%(2/50)。两组比较均有显著性差异(P<0.05)。结论FFN与支原体宫颈炎有关系,对预测羊水胎粪污染及早期治疗胎儿窘迫有价值。Objective： To provide a new method for predicting embassassed embryo, the fetal fibronectin of embryo was determined, the relationship between of mycoplasma cervicitis with amniotic fluid meconium pollution were investigated. Methods ： Enzyme - linked immunosorbent assay was used to examine FFN in vagina secretion for 120 cases of mycoplasma cervicitis and 81 cases of normal pregnant women. FFN ≥50ng/mL is the standard for determining the positive cases. Results： FFN positive cases was 75 and 31, rate is 62. 5% and 38. 2% in treatment and control groups respectively. Amniotic fluid meconium cases was 18 and 2, the positive rate was 24.0% and 4. 0% in treatment and control groups respectively. There has significant difference between two group （ P 〈 0. 05）. Conclusions： The relationship exists between FFN with vagina secretion. It is important to predict amniotic fluid meconium and treat embassassed embryo early.

关 键 词：胎儿纤维连接蛋白 支原体感染 羊水 胎粪污染 

分 类 号：R711.3[医药卫生—妇产科学]