河北省检出脊髓灰质炎疫苗株病毒急性弛缓性麻痹病例流行病学分析  

Analysis on Acute Flaccid Paralysis Cases Induced by Vaccine Derivation Poliomylitis Virus in Hebei Province

作　　者：李静[1] 张振国[1] 张俊棉[1] 张富斌[1] 郭玉[1] 陈玫[1] 

机构地区：[1]河北省疾病预防控制中心,河北石家庄050021

出　　处：《预防医学情报杂志》2009年第7期517-519,共3页Journal of Preventive Medicine Information

摘　　要：目的了解河北省2004-2007年急性弛缓性麻痹(AFP)病例中检出脊髓灰质炎(脊灰)疫苗株病毒阳性病例的流行病学特征。方法描述流行病学方法分析个案数据。结果从1657例AFP病例中检出脊灰病毒91株,检出率为5.5%,均为疫苗相关株病毒。病例散在发生,无聚集性。≤2岁儿童病例占92.3%。临床表现主要以发热、腹泻、肢体感觉障碍、深部腱反射减弱或消失为主。结论脊髓灰质炎疫苗株病毒导致的麻痹病例以2岁以下幼儿多见,应加强监测与研究。Objective To analyze the epidemiological features of acute flaccid paralysis （AFP） cases induced by vaccine derivation poliomyelitis virus （VDPV） from 2004 to 2007 in Hebei Province. Methods Descriptive analysis was conducted on the case data. Results A total of 1 674 AFP cases were reported from 2004 to 2007, and 91 strains of poliovirus were detected （5.5%）, all of them were VDPV. The cases occurred sporadically and children aged ≤ 2 years accounted for 92. 3% of the total cases. The clinical symptoms included fever, diarrhea, sensorial disorder of extremity, weakened or disappeared deep tendon reflect. Conclusion AFP cases induced by VDPV were often observed in children less than 2 years old, it is necessary to strengthen the surveillance and study of AFP cases induced by VDPV.

关 键 词：急性弛缓性麻痹 脊髓灰质炎疫苗株病毒 流行病学分析 

分 类 号：R512.4[医药卫生—内科学]