电针周围性面瘫患者穴位的功能磁共振成像研究  

Electroacupuncturing acupoints of patients with peripheral facial paralysis:a functional MRI study

作　　者：韩俊洲[1,2] 徐海波[1] 唐宏图[3] 王华[3] 官瑾[2] 刘定西[1] 孔祥泉[1] 冯敢生[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院磁共振室,湖北武汉430022 [2]湖北省荆门市第一人民医院CT,磁共振室,湖北荆门448000 [3]湖北中医学院针灸骨伤学院,湖北武汉430061

出　　处：《中国医学影像技术》2009年第7期1167-1170,共4页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金重大研究计划面上项目(90209031)

摘　　要：目的探讨功能磁共振成像(fMRI)研究电针周围性面瘫患者不同穴位时脑功能区变化。方法将18例左侧周围性面瘫患者随机分为3组,分别电针左侧地仓穴(6例)、左侧合谷穴(6例)、左侧后溪穴(6例),同时行全脑fMRI扫描。以SPM软件进行图像后处理,t检验(P<0.05)分析得出电针不同穴位的脑功能图像。结果电针左侧地仓穴、左侧合谷穴信号降低区:双侧额中回,左扣带回;信号升高区:右侧中央前回,双侧中央后回,左侧颞上回,右侧脑岛。电针左侧后溪信号降低区:双侧额下回,左侧豆状核,右侧颞中回,右侧小脑扁桃体;信号升高区:右侧尾状核头,右侧扣带回,脑干,小脑蚓,右侧海马回。结论电针周围性面瘫患者合谷穴和地仓穴可引起大脑相应的功能区激活,而电针后溪穴未见和前两者有相似的激活区域,推测穴位与大脑的联系与其所属的经脉有密切联系。Objective To explore the brain changes of electroacupuncturing （EA） different acupoints of peripheral facial paralysis （PFP） with functional magnetic resonance imaging （fMRI）. Methods Eighteen patients with left PFP were randomly divided into three groups. Six of them received electroacupuncturing left Dicang, 6 received electroacupuncturing left Hegu, and 6 received electroacupuncturing left Houxi. fMRI data were obtained from scanning of the whole brain. Functional data were processed by SPM99 software and functional responses were established with t-test analysis （P〈0.05）. Results Electroacupuncturing Dicang and Hegu on the left induced decreasing of signal in bilateral middle frontal gyrus, left cingulate gyrus, signal increased of right precentral gyrus, bilateral postcentral gyrus, left superior temporal gyrus and right insular, while electroaeupuncturing Houxi on the left induced decrease of signal in bilateral inferior frontal gyrus, left lentiform nucleus, right middle temporal gyrus, right cerebellar tonsil, signal increased of right caudate head, right cingulate gyrus, brainstem, cerebellar vermis and right parahippocampal gyrus. Conclusion Electroacupunctuing Hegu and Dicang can cause corresponding functional activation in cerebrum, while eleetroacupuncturing Houxi can not, suggesting that there is association between cerebral and acupoint of owned meridian.

关 键 词：电针 周围性面瘫 穴位 磁共振成像 

分 类 号：R246[医药卫生—针灸推拿学] R445.2[医药卫生—中医临床基础]