大鼠红核酪氨酸羟化酶、生长抑素和亮啡吠能神经元至延髓外侧网状核的研究  

PROJECTION OF TH-LI,SOM-LI AND L-ENK-LI NEURONS IN RED NUCLEUS TO LATERAL RETICULAR NUCLEUS IN RAT

作　　者：胡祥友[1] 张华[2] 邱实[2] 范天生[2] 

机构地区：[1]安徽医科大学解剖学教研室,合肥230032 [2]河南医科大学解剖学教研室

出　　处：《解剖学杂志》1998年第4期313-316,共4页Chinese Journal of Anatomy

摘　　要：用HRP逆行追踪和免疫细胞化学ABC法相结合研究了红核内酪氨酸羟化酶、生长抑素和亮啡呔免疫活性神经元至延髓外侧网状核的投射.结果表明,红核内HRP标记细胞为对侧性,主要分布于其尾侧2/3,同时,还可见酪氨酸羟化酶、生长抑素、亮啡呔单标细胞及HRP/酪氨酸羟化酶、HRP/生长抑素、HRP/亮啡呔双标细胞,其中HRP/酪氨酸羟化酶双标细胞约占HRP单标细胞25.2%,HRP/生长抑素双标细胞约占21.3%,HRP/亮啡呔双标细胞约占15.4%.红核参与镇痛和心血管活动的调节可能与上述神经递质有关.The projection of tyrosine hydroxylase-like immunoreactive (TH-LI), somatostatin-like im-munoreactive (SOM-LI) and Leucine-enkephalin-like immunoreactive (L-ENK-LI) neurons in red nucleus to lateral reticular nucleus was demonstrated by horseradish peroxidase(HRP) retrograde tracing and immunocytochemical avidin-biotin-peroxidase complex (ABC) methods. Seven kinds of labeled neurons were found: HRP labeled neurons, TH-LI, SOM-LI, L-ENK-LI neurons, HRP/TH, HRP/SOM and HRP/L-ENK double-labeled neurons. The percentage of HRP/ TH double-labeled neurons in the total number of HRP labeled neurons were 25. 2%, of HRP/ SOM double-labeled neurons 21. 3% ,and of HRP/L-ENK double-labeled neurons 15. 4% respectively. These neurotransmitters may be involved in the regulation of the analgesia and cardiovascular system in the red nucleus.

关 键 词：红核 外侧网状核 神经元 延髓 酪氨酸羟化酶 

分 类 号：R322.8[医药卫生—人体解剖和组织胚胎学] R338.22[医药卫生—基础医学]