大容量肺灌洗治疗煤工尘肺肺功能远期效果的观察——附90例报告  

Long-term therapeutic effects observation of large volume lung lavage on lung function of coal workers'pneumoconiosis

作　　者：袁扬[1] 黄京慧[1] 马国宣[1] 陈刚[1] 刘贺[1] 张志浩[1] 陈志远[1] 

机构地区：[1]国家煤矿安全监察局尘肺病康复中心

出　　处：《中国疗养医学》2009年第8期677-679,共3页Chinese Journal of Convalescent Medicine

基　　金：中国煤矿尘肺病治疗基金会资助项目(2008-02)

摘　　要：目的通过对大容量肺灌洗(WLL)治疗煤工尘肺远期肺功能效果的分析,来探讨WLL治疗和控制尘肺病的效果。方法选择陕西省韩城矿务局某煤矿,采用回顾性队列研究的方法,日本捷斯特(CHEST)肺功能仪作为检测仪器,对入列现存活的90例(肺灌洗组21例,非肺灌洗组69例)Ⅰ期煤工尘肺患者的肺功能进行横断面检测;将肺灌洗组和非肺灌洗组患者的肺功能按VC,FVC,FEV1,FEV1%,MMF,PEF,FEF25,FEF50,FEF75,MVV等10个指标进行比较分析。结果肺灌洗组在PEF、FEF25及MVV指标检测结果分别为50.6±28.5,49.2±26.7,72.6±34.8;非肺灌洗组分别为30.8±16.2,30.8±17.3和49.0±20.0,两组比较,肺灌洗组好于非肺灌洗组,差异有统计学意义(P<0.05);其他指标两组比较,差异无统计学意义(P>0.05)。结论WLL对尘肺患者的远期肺功能有一定的改善,是尘肺病治疗及二级预防的一种有效方法。Objective To analyse long-term therapeutic effects of large volume lung lavage on lung fimction of coal workers＇pneumoconiosis, discuss treatment effect of WLL and pneumoconiosis. Methods Through retrospective cohort study, 90 existing patients with I stage coal worker＇s pneumoconiosis fi＇om one coal mine of Hancheng Coal Mining Administration, Shaanxi Province were selected and divided into lung lavage group（21case ） and non-lung lavage grooup（69cases） .The lung functions of all patients were measured by Japan CEEST lung functional apparatus through cross-section study.Ten parameters such as VC,FVC,FEV1, FEV1%, MMF, PEF, FEF25, FEFso, FEF75 and MVV were compared and analyzed in two groups. Results PEF, FEF25 and MVV were （50.6± 28.5）,（49.2±26.7）,（72.6±34.8） respectively in the lung lavage group,and （30.8±16.2）,（30.8±17.3） and （49.0±20.0） respectively in the non-lung lavage group.These parameters in the lung lavage group were superior than that in the non- lung lavage group,there was statistical significance between them.There were no significant difference of other parameters between the two groups. Conclusion Large volume lung lavage can improve long-term lung function.lt is an effective method for the treatment of pneumoconiosis and the second level prevention.

关 键 词：大容量肺灌洗 肺功能 远期效果 

分 类 号：R135.2[医药卫生—劳动卫生] R563[医药卫生—公共卫生与预防医学]