受试者特征曲线评价心肌酶谱对急性心肌梗死的诊断价值  

APPLICATION OF RECEIVER OPERATING CHARACTERISTIC CURVE TO EVALUATE MYOCARDIAL ENZYMES' EFFECTS ON IDENTIFICATION OF ACUTE MYOCARDIAL INFARCTION

作　　者：高峰[1,2,3] 彭 王仁安 

机构地区：[1]北京医科大学第一医院医学统计室 [2]北京市第六医院内科 [3]北京医科大学卫生统计学教研室

出　　处：《北京医科大学学报》1998年第4期345-347,共3页Journal of Peking University(Health Sciences)

摘　　要：目的：了解心肌酶谱对急性心肌梗死的诊断价值。方法：应用受试者特征（ＲＯＣ）曲线对１２９例急诊怀疑为急性心肌梗死的发病２４ｈ内就诊患者进行评价。结果：（１）急性心肌梗死组患者心肌酶谱各指标的平均水平均高于非急性心肌梗死组患者；（２）各指标的ＲＯＣ曲线下面积以肌酸激酶同工酶ＣＫＮＡ为最大（Ａ＝０．８７３），其余各项指标的面积介于０．７１２至０．７５８之间。结论：除ＣＫＮＡ具有较高的诊断价值外，其余各项指标的诊断价值不大。ＣＫＮＡ似以１６０ｕ作为诊断参考值最佳，此时灵敏度为８５．１％，特异度为８２．３％。ABSTRACT Objective: To understand the diagnostic effects of myocardial enzymes towards acute myocardial infarction (AMI). Methods: By using the receiver operating characteristic curve, this essay evaluates the diagnostic effects of myocardial enzymes to 129 cases who were suspected of AMI and attacked within 24 hours. Results: (1) The average levels of all myocardial enzymes in AMI group are higher than those in nonAMI group. (2) CKNA has the highest undercurve area (A=0.873), and the areas of other items range from 0.712 to 0.758. Conclusion: Only CKNA shows a satisfied diagnostic effect, and it seems that the best cutoff point may be 160 unit which generates a sensitivity of 85.1% and a specificity of 82.3%.

关 键 词：心肌梗塞 AMI 诊断 心肌酶谱 ROC曲线 

分 类 号：R542.220.4[医药卫生—心血管疾病]