宿主自身卵巢对移植胚鼠卵巢生长发育影响的实验研究  

Influence of local ovaries on the growth of transplanted fetal ovaries in rats

作　　者：黄学惠[1] 秦海燕[1] 马方[1] 

机构地区：[1]昆明医学院第一附属医院妇科,650032

出　　处：《实用医学杂志》2009年第15期2428-2429,共2页The Journal of Practical Medicine

基　　金：云南省教育厅科学基金资助项目(编号:4041163)

摘　　要：目的:探讨宿主自身卵巢与移植胚鼠卵巢的生长发育是否存在相互影响的关系。方法:将胚鼠卵巢分别移植至单侧卵巢摘除及去势雌鼠皮下,观察同时存在的自身卵巢对移植卵巢生长发育有无影响,以及自身卵巢是否受移植卵巢影响。结果:单侧卵巢摘除宿主卵巢黄体总体均数较高,差异有统计学意义(F=11.611,P=0.001)。去势宿主体内移植的胚胎卵巢中的原始卵泡会继续生长发育出各阶段卵泡,而单侧卵巢摘除者体内的移植停止发育,抑或纤维化吸收。结论:宿主体内卵巢与移植胚鼠卵巢卵泡存在相互竞争关系,自身卵巢较移植物卵泡更具优势。Objective To investigate the interaction on growth between local ovaries and transplanted fetal ovaries in rats. Methods Fetal ovaries were transplanted to rats who had received unilateral ovarian extirpation （group A） or oophorotomy （group B）, and then the interaction between local ovaries and transplanted ovaries was detected. Result Number of orpus luteum of local ovaries was higher in group A as compared with those of transplanted ovaries in group A and group B （F = 11.611, P = 0.001）. Follicles in transplanted ovaries could grow to different stages in group B, but were stopped and absorbed in group A. Conclusion There exists competitive correlation between local ovaries and transplanted fetal ovaries, and local ovaries have a advantage over transplanted ovaries.

关 键 词：卵巢 异位移植 大鼠 生殖 内分泌 

分 类 号：R713[医药卫生—妇产科学]