阿尔茨海默病与个人社会网络关系病例对照研究  

Effect of social network on Alzhemer's disease:a case-control study

作　　者：王艳[1] 黄文湧[1] 杨敬源[1] 杨星[1] 汪俊华[1] 邓厚才[1] 韩志琰[1] 

机构地区：[1]贵阳医学院公共卫生学院流行病学教研室,贵阳550004

出　　处：《中国公共卫生》2009年第8期932-934,共3页Chinese Journal of Public Health

基　　金：贵州省省长资金(黔科教办[2004]07);贵州省教育厅自然科学研究项目(黔教科2005108)

摘　　要：目的探讨阿尔茨海默病(AD)与个人社会网络的关系。方法在2004～2005年贵州省贵阳市城区老年期痴呆流行病学调查结果的基础上,采用成组病例对照研究,对可能的AD社会网络影响因素进行分析。采用χ2检验和非条件Logistic回归分析。结果病例组41例,平均年龄(77.20±8.6)岁,对照组2524人,平均(69.82±7.0)岁。在控制了年龄和受教育程度后,子女看望频率高者(≥1次/周)患AD的危险性小(OR=0.26,95%CI=0.07～0.94);非独居者比独居者患AD的危险性小(OR=0.37,95%CI=0.18～0.76);与拥有不良的社会网络者比较,具有丰富的社会网络者患AD风险最低(OR=0.06,95%CI=0.007～0.60)。结论社会网络对AD的发生有明显影响,具有丰富的社会网络有助于AD预防。Objective To explore the effect of social network on Alzheimer＇s disease（AD） among the elderly. Methods The data were Collected from a cross-sectional study conducted in a community population of Guiyang city. A case-control study was made to analyze the effect of social network on AD. Data analysis was conducted with X2 test and non-conditional logistic regression. Results After adjusting for age and education,old people who met their children more than once a week had a lower risk of AD （ OR = 0. 26,95 % CI = 0. 07 -0. 94）. Significantly lower risk of AD was existed in the elderly living with others（ OR = 0. 37,95% CI = 0. 18 - 0. 76）. Compared with a poor social network, an extensive social network led to the lowest risk of AD among the elderly（ OR = 0. 06,95% CI = 0. 007 - 0. 60）. Conclusion There is a close association between social network and AD. An extensive social network may be heplful to prevent AD.

关 键 词：社会网络 阿尔茨海默病(AD) 老年人 病例对照研究 

分 类 号：R195[医药卫生—卫生统计学]