两种通气模式对健康和急性肺损伤犬心肺功能影响的比较  

COMPARISON BETWEEN EFFECTS OF IRV ANDAPRV VENTILATORY MODES ON CARDIAPULMONARYFUNCTION IN HEALTHY AND ACUTE LUNG INJURY DOGS

作　　者：方智野[1] 白春学[1] 宋元林[1] 洪群英[1] 钮善福[1] 

机构地区：[1]上海医科大学中山医院肺科

出　　处：《上海医科大学学报》1998年第4期265-268,共4页Journal of Fudan University(Medical Science)

摘　　要：比较容量控制反比通气（ＶＣ－ＩＲＶ，简称ＩＲＶ）和气道压力释放通气（ＡＰＲＶ）模式对健康和急性肺损伤（ＡＬＩ）犬心肺功能的影响。方法对健康和ＡＬＩ模型（犬），分别用ＩＲＶ和ＡＰＲＶ模式进行通气，观察通气期间血流动力学、血气、呼吸生理的变化。结果对于健康犬在气道峰压相似的情况下，ＡＰＲＶ模式时平均气道压和肺动脉压显著高于ＩＲＶ时。对血流动力学、血气和呼吸力学的影响两者差别不显著。ＡＰＲＶ模式下氧运输量和ＰａＯ２／ＦｉＯ２值较ＩＲＶ对显著高。对于ＡＬＩ犬ＡＰＲＶ时的气道峰压显著低于ＩＲＶ时，平均气道压两者相似，ＰａＯ２／ＦｉＯ２则是ＡＰＲＶ时显著高于ＩＲＶ时。结论ＡＰＲＶ与ＩＲＶ相比，前者氧合功能显著优于后者，且气道峰压较低，更适用于ＡＬＩ者。おURPOSE In order to compare the effects of cardiac-pulmonary function in health and acute lung injury (ALI) dogs by inverse ration ventilation (IRV) and airwary pressure release ventilation (APRV) ventilatory modes.METHODS Two different ventilatory modes, volume control IRV and APRV were given to ten health and ALI dogs. During ventilation, the parameters of hemodynamics, blood gas and respiratory physiological indices were recorded.RESULTS For the health dogs, when the peak airwary pressure were simillar, the mean ariwary pressure of APRV was notably higher than that of IRV, while their effects on hemodynamics and blood gas were simillar. For ALI dogs, the peak airwary pressure of APRV was significantly lower and PaO2/FiO2 significantly higher than that of IRV, while the mean airwary pressure of two modes were simillar.CONCLUSIONS The oxygenation of APRV is better than that of IRV, and with lower peak airway pressure, APRV is more fit for ALI patients.

关 键 词：容量控制 反比通气 肺损伤 心肺功能 

分 类 号：R563.05[医药卫生—呼吸系统] R459.6[医药卫生—内科学]