糖原磷酸化酶同工酶BB在早期急性冠脉综合征的诊断价值  

Diagnostic valume of glycogen phosphorylase isoenzyme BB (GPBB) in early acute coronary syndrome

作　　者：卫波[1] 余猛进[1] 石正蒙[1] 丁晓辉 李林 

机构地区：[1]上海市浦东新区人民医院急诊科,201200 [2]上海凯创生物技术有限公司

出　　处：《江苏医药》2009年第8期908-909,共2页Jiangsu Medical Journal

基　　金：上海市浦东新区卫生系统优秀学科带头人计划(PWRd200606)

摘　　要：目的探讨糖原磷酸化酶同工酶BB(GPBB)快速检测试剂条在急性冠脉综合征(ACS)早期诊断中的意义。方法比较心肌肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)及GPBB快速检测试剂条检测发病6h内拟诊ACS患者的差别。结果GPBB快速检测法对ACS的诊断敏感性高于CK-MB和cTnI(88.12%vs.57.43%and70.30%,P<0.05),特异性高于CK-MB(95.65%vs.78.26%,P<0.05)。结论GPBB可快速准确检测早期ACS。Objective To evaluate the significance of glycogen phosphorylase isoenzyme BB （GPBB） rapid test in the early diagnosis of acute coronary syndrome （ACS）. Methods The efficaeies of cardiac troponin I （cTnI）,creatine kinase isoenzyme （CK-MB） and GPBB reagent strips for rapid test in diagnosis of ACS diagnosed in 6 h were compared. Results In the diagnosis of ACS, the sensitivity of GPBB rapid test assay was significantly higher than that of CK-MB and cTnI（88. 12% vs. 57.43% and 70. 30%,P〈0. 05） and the specificity of it was higher than CK-MB（95.65% vs. 78.26% ,P〈0.05）. Conclusion GPBB may be used for rapidly and accurately diagnosing ACS.

关 键 词：糖原磷酸化酶同工酶BB 急性冠脉综合征 

分 类 号：R543[医药卫生—心血管疾病]