Ag nanoparticles sensitize IR-induced killing of cancer cells  

作　　者：Ruizhi Xu Jun Ma Xinchen Sun ZhongpingChen Xiaoli Jiang Zhirui auo Lan Huang YangLi Meng Wang Changling Wang Jiwei Liu XuFan Jiayu Gu Xi Chen Yu Zhang Ning Gu 

机构地区：[1]School of Biological Science and Medical Engineering, Jiangsu Laboratory for Biomaterials and Devices, State Key Laboratory of BioElectronics, Southeast University, Nanjing 210096, China [2]Clinical college of Southeast University, Nanjing 210019, China [3]Tumor Center of Zhongda Hospital, Southeast University, Nanjing 210019, China [4]The Institute of Cardiovascular Disease, Division ated Hospital of Nanjing Medical China of Medicine, the First Affili- University, Nanjing 210029,

出　　处：《Cell Research》2009年第8期1031-1034,共4页细胞研究（英文版）

摘　　要：Dear Editor, Nanosized particulate systems combining better cancer diagnosis with therapeutic effect are being designed based on the merging of nanotechnology with cellular and molecular techniques. The surface of these nanoscale carriers is often functionalized with biological molecules for stabilization and targeted delivery. The combinations of nano-core and associated functional molecules can cross the cell membrane [1], and the surface of nanomaterials （including coating and associated functional molecules） plays a critical role in determining the outcome of their interactions with cells [2, 3]. Studying the potential effects of nanomaterials in biological systems often requires the administration of nanoparticles into a cell culture system or into living organisms in vivo. It should be noted, however, that under such conditions nanopaticles are known to adsorb proteins from the biological system,

关 键 词：银纳米粒子 癌细胞 诱导 敏感 红外 细胞融合技术 生物分子 载体表面 

分 类 号：Q279[生物学—细胞生物学] O614.122[理学—无机化学]