抗体效价测定及诊断性治疗在肺炎支原体感染诊治中的应用  

Application of determination of antibody titer and diagnostic treatment in mycoplasma pneumonia

作　　者：游春萍[1] 

机构地区：[1]广东省东莞市莞城医院,523000

出　　处：《齐齐哈尔医学院学报》2009年第14期1671-1672,共2页Journal of Qiqihar Medical University

摘　　要：目的探讨临床诊断和抗体效价测定及诊断性治疗联合分析在肺炎支原体感染早期诊治中应用的意义。方法对东莞市莞城医院儿科381例住院患儿中首次临床诊断为肺炎支原体感染病例,均作肺炎支原体抗体效价测定及希舒美诊断性治疗,并分析抗体效价测定阳性及希舒美诊断性治疗有效率。结果381例住院患儿肺炎支原体抗体效价测定阳性为103例,阳性率为27%,阴性率为73%。希舒美治疗有效共312例,有效率为81.9%,无效率为18.1%。对临床诊断为支原体感染同时抗体效价阳性的103例中,希舒美治疗有效为93例,有效率为90.3%。抗体效价测定为阴性的278例中,希舒美治疗有效为219例,有效率为78.8%。结论临床诊断成立、抗体效价测定阳性及诊断性治疗有效三者中只要其中两者成立,可从临床上诊断肺炎支原体感染,为肺炎支原体感染的早期诊断提供一个新的重要参考方法。Objective To evaluate the efficacy of determination of antibody titer combined with diagnostic treatment in the treatment of early stage of mycoplasma pneumonia. Methods Determination of antibody titer and diagnostic treatment were performed in 381 patients with mycoplasma pneumonia in Guancheng Hospital of Dongguan. Results The positive rate of antibody titer was 27% ; the effective rate of Zithromax was 81.9% （312/381）. In 103 patients with positive antibody titer and clinical diagnosis, the effective rate of Zithromax was 90.3%（93/381）. In 278 patients with negative antibody titer, the effective rate of Zithromax was 78.8%（219/381）. Conclusions Among clinical diagnosis, positive antibody titer and diagnostic treatment, if the patient conforms to two of them, the diagnosis could be established; it is helpful for the early diagnosis of mycoplasma pneumonia.

关 键 词：肺炎支原体 抗体 测定 希舒美 

分 类 号：R725.631[医药卫生—儿科] R457.11[医药卫生—临床医学]