腹膜透析患者钙磷代谢紊乱43例临床分析  

The Disorders of calcium and phosphors metabolism in peritoneal dialysis patients

作　　者：翁敏 白云凯[1] 韩晓玲[1] 扬荆[1] 

机构地区：[1]昆明医学院第一附属医院肾内科,昆明650031

出　　处：《陕西医学杂志》2009年第8期996-998,共3页Shaanxi Medical Journal

基　　金：云南省教育厅资助项目(5Y0468C)

摘　　要：目的:探讨持续性不卧床腹膜透析(CAPD)患者残肾功能,腹膜透析的充分性和腹膜转运特性对钙磷代谢的影响。方法:连续不卧床腹膜透析患者43例,透析时间3.5～34个月,透析剂量6～8L/d。用腹膜平衡试验测定腹膜转运功能。以残肾GRF>2ml/min为有残余肾功能的界线。所有患者以尿素清除指数(kt/v)≥1.7和肌酐清除率(Ccr)≥50L/周.173m2为透析充分的最低标准。结果:没有残肾功能的患者血磷和钙磷乘积较有残肾功能者明显升高。结论:CAPD患者普遍存在钙磷代谢紊乱,以血磷和钙磷乘积升高较明显,残存肾功能对血磷的清除起着重要的作用。Objective：To investigate the influence of residual renal function, abundance of dialysis and peritoneal membrane transport capacity on the calcium and phosphorus metabolism in continued ambulatory peritoneal dialysis patients （CAPD）. Methods：Forty three patients undergoing CAPD from 3. 5- 34 months with dialysis dosage 6 - 8L/d were researched peritoneal function characteristics using the peritoneal equilibration test（PET）. The residual renal function of the CAPD patients was set a target minimum of 2ml/ rain. The most minimal standard about the abundance of dialysis was that （kt/v） ≥1.7 and Ccr 〉50L/week. 173m^2 to all of the subjects in this test. Results： The patients who had not owned residual renal function had significant elevated serum phosPhorus level and value of （CA^2＋） ＊ （p^2＋）（p〈0. 05）. Conclusion：Disorders of calcium and phosphorus metabolism, especially hyper serum phosphorus and higher calcium-phosphorus product are common in CAPD patients. The residual renal function plays an important role in the clearance of serum phosphorus.

关 键 词：尿毒症/病理生理学 代谢疾病/病因学 肾透析/方法 钙 磷 

分 类 号：R459.5[医药卫生—治疗学] R656.41[医药卫生—临床医学]