体外受精-胚胎移植中多胎减胎后双胎妊娠结局的比较  

Pregnany outcome analysis of twin pregnancies and twins pregnancies of multifetal reduction in IVF/ET

作　　者：裴莉[1] 叶虹[1] 曾品鸿[1] 罗秀[1] 

机构地区：[1]重庆市妇幼保健院生殖与遗传研究所,400013

出　　处：《重庆医学》2009年第16期2007-2008,2010,共3页Chongqing medicine

摘　　要：目的分析体外受精-胚胎移植(IVF-ET)中多胎妊娠减胎术对双胎妊娠结局的影响。方法回顾性分析了IVF-ET后直接双胎妊娠492例(A组)和IVF后3胎妊娠减为双胎妊娠26例(B组)、IVF后3胎妊娠中自减为双胎妊娠22例(C组)的妊娠结局。结果A组早期流产率为6.5%,B组早期流产率为11.5%,C组早期流产率为4.5%,晚期流产率A组为4.7%,B组为7.7%,C组为9.1%;A、B两组之间早期流产率差异有统计学意义(P<0.05),A组与C组比较晚期流产率差异有统计学意义(P<0.05)。3组平均年龄、平均孕周、剖宫产率、早产率之间差异无统计学意义(P>0.05)。结论IVF-ET中多胎减为双胎妊娠与IVF-ET中直接双胎妊娠比较,早期流产率明显增加。Objective To analyse the effect of twins of multifetal reduction in IVF/ET on the pregnancy outcome of twin pregnancies. Methods A retrospective study was carried out to measure miscarriage rate, premature delivery rate, neonatal mortality rate,malformation rate and mean gestational age in the patients of twin pregnancy（group A,n=492） and multifetal pregnancy reduced to obtain twins（group B,n=43） undergoing IVF. Results There was no significant difference in the pregnant complications, premature delivery rate, malformation rate, neonatal mortality rate and mean gestational age between group A and B,while more significant in early abortion rate. Conclusion Selective reduction increases early abortion rate.

关 键 词：双胎妊娠 IVF-ET 减胎术 多胎减胎 

分 类 号：R714.8[医药卫生—妇产科学]