正交设计法优选假马齿苋中总皂苷提取工艺  

Study on extraction technology of total saponins in Bacopa monnieri by orthogonal design

作　　者：毛一亮 巫军 丁萍月 张佳佳[3] 杨雄志[3] 

机构地区：[1]浙江奉化市第二医院,宁波315502 [2]浙江宁波拜奥生物,宁波315200 [3]浙江医药高等专科学校,宁波315000

出　　处：《海峡药学》2009年第7期38-40,共3页Strait Pharmaceutical Journal

基　　金：国家创新基金资助(07C26213311429)

摘　　要：目的研究假马齿苋中总皂苷的提取工艺。方法采用正交试验法,以总皂苷含量为考察指标,优化假马齿苋中总皂苷的提取工艺。结果最佳提取工艺为1∶20倍煎药液得量,回流提取2次,每次3小时。结论该试验工艺稳定,重现性好。OBJECTIVE To optimize extraction technology of total saponins in Bacopa monnieri. METHODS The extraction technology was optimized by orthogonal design, while total saponins were adopted as index. RESULTS AND CONCLUSIONS The best extraction conditions were 20-fold water, 3 hours of reflux, and 2 times of extraction. This technology is stable and practical.

关 键 词：假马齿苋 总皂苷 正交设计 

分 类 号：TQ460.4[化学工程—制药化工]