糖尿病性肝病23例临床研究  

Clinical study of 23 cases of Diabetic liver disease

作　　者：邓婷婷[1] 

机构地区：[1]广西医科大学第四附属医院,柳州市545005

出　　处：《内科》2009年第4期531-533,共3页Internal Medicine

摘　　要：目的研究糖尿病性肝病(DLD)的发病机制、临床、病理特点及诊断治疗。方法选取糖尿病性肝病组患者23例,采用胰岛素强化治疗方法,观察该组患者治疗前后的临床表现及测定各项生化指标、B超及肝穿病理活检,并与非糖尿病肝病外科手术组患者肝组织病理10例作比较。结果糖尿病肝病组治疗2疗程以上,肝功能均恢复正常。肝穿组织病理检查胞浆中糖原颗粒减少,糖原空洞消失。非糖尿病肝病外科手术组肝组织病理均未见核内糖原空洞,胞浆糖原较糖尿病肝病组少。结论小剂量胰岛素静脉滴注治疗糖尿病肝病,不但能较快控制血糖,还能使肝功能好转,肝肿大减轻甚至恢复正常。Objective To study the pathogenesis, clinical and pathological features, diagnosis and treatment of diabetic liver disease （DID）. Methods 23 cases of the DLD received intensive insulin therapy, the clinical manifestations and various biochemical indexes, B-ultrasound and liver biopsy were observed, and 10 cases of non-diabeties with liver pathology wear for comparison. Results DLD groups ：liver function returned to normal after two or more courses of treatment,liver biopsy pathological examination showed the reduction of glycogen granules and disappeared of glycogen hollow. In non-diabetic group, liver pathology showed no nuclear glycogen empty in cytoplasm, cytoplasm glycogen was less than in DLD. Conclusion Low-dose insulin infusion treatments of DLD, Which not only rapidly control of blood glucose,improve liver function, reduce hepatomegely or even back to normal.

关 键 词：糖尿病性肝病 血糖 核内糖原空洞 胰岛素 

分 类 号：R587.2[医药卫生—内分泌] R575[医药卫生—内科学]