老年人和青年人咀嚼前后脑血流变化的对照研究  

The study of cerebral blood flow before and after mastication in aged and young

作　　者：肖瑞[1] 刘洪臣[1] 邵龙泉[1] 

机构地区：[1]解放军总医院口腔医学中心,北京100853

出　　处：《临床口腔医学杂志》2009年第8期454-456,共3页Journal of Clinical Stomatology

基　　金：国家自然科学基金项目(30572066);首都医学发展科研基金重点项目(2003-2018)

摘　　要：目的:通过对老年人和青年人咀嚼前后脑血流变化的对照研究,观察咀嚼运动对脑血流的影响。方法:应用经颅多普勒超声诊断仪探测老年人和青年人大脑中动脉的收缩期峰流速、舒张期末峰流速及平均峰流速,进行方差分析。结果:两组受试者在咀嚼5min后、咀嚼10min后的收缩期峰流速、舒张期末峰流速及平均峰流速均高于咀嚼前,并有显著性差异(P<0.05)。在各时间段上,老年人除在舒张期峰流速均数低于青年人外,在收缩期峰流速均数和平均峰流速均数与青年人无显著性差异。结论:老年人正常咀嚼功能时脑血流指标趋向与青年组脑血流指标相似,提示咀嚼运动对老年人脑血流量增加同样有促进作用。Objective：To study the influence of mastication on the cerebral blood flow through the control research of changes of cerebral blood flow before and after mastication in aged and young. Method： The systolic peak flow, diastolic terminal peak flow and average peak flow in cerebral middle artery were measured with the use of Transcranial Doppler ultrasonic diagnostic instrument. Result： The systolic peak flow, diastolic peak flow and average peak flow had increased after masticated 5 minutes and 10 minutes （P〈0.05）. In every period, the average diastolic peak flow in aged group was lower than that in young group. The averaged systolic peak flow and the average peak flow were no signicantly difference between two groups. Conclusion： This suggests that normal masticatory function could relieve the effect of age on cerebral blood flow and the intergrity of the dentition should be preserved and restored as far as possible.

关 键 词：咀嚼 脑血流 脑功能 

分 类 号：R333.1[医药卫生—人体生理学]