超临界CO_2从南海翡翠贻贝中萃取EPA和DHA的研究  

Study on Extraction of Eicosapentaenoic Acid and Docosahexaenoic Acid from Jadeite Mussel of South China Sea by Supercritical CO 2

作　　者：宋启煌[1] 姚煜东[1] 张穗[1] 庆宁 周家华[1] 宋照斌[1] 

机构地区：[1]广东工业大学化工系

出　　处：《精细化工》1998年第4期51-54,共4页Fine Chemicals

基　　金：广东省科学基金

摘　　要：用超临界ＣＯ２对南海翡翠贻贝中萃取二十碳五烯酸（ＥＰＡ）和二十二碳六烯酸（ＤＨＡ）工艺进行了研究，得出其最佳工艺条件为：压力３５ＭＰａ，温度３５℃，ＣＯ２用量２ｍｌ／ｇ料，尿素用量为乙酯量的１０％。乙酯的萃取率达到６１．５％。ＥＰＡ和ＤＨＡ乙酯总含量（ｗ）达到２８３２％。The technology of extraction of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from Jadeite Mussel of South China Sea by supercritical CO 2 is studied.The optimum technological conditions are defined as follows:pressure is 35MPa,temperature is 35℃,every gram of raw material consumes 2ml of CO 2,consumption of urea is 10% of ethyl ester.The highest extraction rate of ethyl ester can reach 61.5%.Total mass fraction of EPA and DHA can give 28.32%.

关 键 词：超临界 翡翠贻贝 萃取 EPA DHA 二氧化碳 药物 

分 类 号：TQ225.5[化学工程—有机化工] R915[医药卫生—微生物与生化药学]