植物环肽及其可能的生物合成途径(英文)  

Plant Cyclopeptides and Possible Biosynthetic Mechanisms

作　　者：杜良成[1] 谭宁华[2] 许文彦[1,2] 娄丽丽[1] 

机构地区：[1]内布拉斯加州立大学林肯分校化学系,林肯内布拉斯加68588 [2]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南昆明650204

出　　处：《云南植物研究》2009年第4期374-382,共9页Acta Botanica Yunnanica

基　　金：supported by NSF(MCB-0614916);NIH(AI073510);Nebraska Research Initiatives and NSFC(No.30428023);supported by NSFC(30725048,China-Australia Special Fund for S&T Cooperation)

摘　　要：植物环肽是一个庞大的小分子天然产物家族,通常由4～10个氨基酸残基组合而成。该类化合物广泛存在于全球多种植物的根、茎、枝、叶及种子中,中草药中也时有发现。由于对其生物合成途径及机理研究较少,环肽分子的利用价值尚未得到有效的开发。和常见的非环状基因编码的多肽或蛋白质相比,环肽结构更为复杂。本文将对植物环肽的生物合成途径及其机理做初步探讨。Plant eyclopeptides are a large group of small molecular weight natural produets, typically with 4-10 amino acids, isolated from the leaves, stem barks, roots, and seeds of a wide variety of plant species throughout the world. The peptides are present in many Chinese medicinal plants, and their potentials have not been well exploited because of the lack of knowledge in their biosynthetic origin and mechanism. The cyclopeptides often have complex chemical structures distinct from common palypeptides （proteins） that are non-cyclic and gene-coded. This review discussed the potential origin of the cyclopeptides and their possible biosynthetic mechanisms.

关 键 词：植物环肽 生物合成 内生菌 非核糖体环肽 

分 类 号：Q946.1[生物学—植物学]