独一味与糙苏中环烯醚萜苷类成分的比较  

Comparison the iridoid glycosides between Lamiophlomis rotata and Phlomis umbrosa.

作　　者：尚小飞[1,2] 李茂星[2] 樊鹏程[2] 尉丽力[2] 张汝学[2] 贾正平[1,2] 

机构地区：[1]兰州大学生命科学学院,甘肃兰州730000 [2]兰州军区兰州总医院,甘肃兰州730050

出　　处：《华西药学杂志》2009年第4期391-393,共3页West China Journal of Pharmaceutical Sciences

基　　金：全军中医药研发推广项目(2006032001);甘肃省科技攻关项目(2GS054-A43-014-14)

摘　　要：目的比较独一味与糙苏中的环烯醚萜苷类成分。方法采用TLC法鉴别独一味与糙苏药材中的环烯醚萜苷类成分,建立HPLC法测定其中的8-乙酰氧基山栀子苷甲酯的含量。结果糙苏及独一味均含有大量的环烯醚萜苷类成分,两者根部具有十分相似的薄层色谱图、地上部分及根部中8-乙酰氧基山栀子苷甲酯的含量分别为17.41、0.5、6.81、8.50 mg.g-1。结论独一味根与糙苏根中含有相近的环烯醚萜苷类成分。OBJECTIVE To compare the iridoid glycosides between Lamiophlomis rotata and Phlomis umbrosa.METHODS Thin layer chromatography（TLC） was used to identity iridoid glycosides between L.rotata and P.umbrosa and HPLC was used to determine the content of 8-O-acetylshanzhiside methylester in the roots and aerial parts of these two medicinal materials.RESULTS L.rotata and P.umbrosa contained plenty of iridoid glycosides and showed similar chromatograms.The content of 8-O-acetylshanzhiside methylester in the aerial parts of L.rotata and P.umbrosa were 17.42 mg·g^-1 and 0.5 mg·g-1,6.81 mg·g^-1 and 8.50 mg·g^-1 in the roots respectively.CONCLUSION The roots of L.rotata and P.umbrosa contain similar iridoid glycosides.

关 键 词：环烯醚萜甘 独一味 糙苏 薄层色谱 高效液相色谱法 8-乙酰氧基山栀子苷甲酯 

分 类 号：R917[医药卫生—药物分析学]