钾离子通道在肺动脉高压中的作用研究进展  

Study Progress of Potassium Channel in Pulmonary Artery Hypertension

作　　者：韩玉兰[1] 庞玉生[1] 

机构地区：[1]广西医科大学第一附属医院儿科,南宁530021

出　　处：《实用儿科临床杂志》2009年第13期1029-1031,共3页Journal of Applied Clinical Pediatrics

摘　　要：肺动脉高压(PAH)是多种因素引起的肺血流动力学异常,以肺血管阻力进行性升高为临床特征的一组疾病。近年研究表明,肺动脉平滑肌细胞膜上的钾离子通道与PAH时的肺血管收缩和血管重构关系密切,现就钾离子通道在PAH中的作用研究进展作一综述。Pulmonary artery hypertension （PAH） is a combination of factors caused abnormal pulmonary hemodynamics.Pulmonary vascular resistance （PVR） progressive as clinical features of PAH.In recent years,studies had shown that pulmonary artery smooth muscle cell membrane potassium channels at the time of PAH and pulmonary vasoconstriction （HPV） and vascular remodeling were closely related to potassium channel in the article on the role of PAH in progress of the study review.

关 键 词：肺动脉高压 钾离子通道 膜电流 

分 类 号：R543.2[医药卫生—心血管疾病]