曲司氯铵与盐酸黄酮哌酯治疗膀胱痉挛的疗效比较  

Efficacy of Trospiumchloride vs.Flavoxate Hydrochloride for Cystospasm

作　　者：赵泽驹[1] 陆立[1] 罗旭[1] 

机构地区：[1]遵义医学院附属医院,遵义市563003

出　　处：《中国药房》2009年第23期1794-1795,共2页China Pharmacy

摘　　要：目的:探讨曲司氯铵治疗膀胱痉挛的疗效。方法:前列腺增生与膀胱病变术后发生膀胱痉挛的患者86例,随机分为2组,分别用曲司氯铵和盐酸黄酮哌酯治疗至术后1周。比较膀胱痉挛的发生频率、严重程度和不良反应。结果:曲司氯铵控制膀胱痉挛的效果显著优于盐酸黄酮哌酯(P<0.01)。结论:曲司氯铵可有效地抑制经膀胱和膀胱手术后膀胱痉挛的发生。OBJECTIVE： To observe the clinical efficacy of Trospiumchloride for cystospasm. METHODS： 86 patients with cystospasm after undergoing prostatic operation or the operation on bladder were randomly assigned to receive either Trospiumchloride or Flavoxate Hydrochloride for 1 week. The incidence and the severity of cystospasm and the adverse drug reaction were compared between the two groups. RESULTS： Trospiumchloride was significantly better than flavoxate hydrochloride in clinical efficacy for cystospasm（P〈0.01） . CONCLUSION： Trospiumchloride can effectively inhibit the cystospasm in patients undergoing transvesical operation or operation on bladder.

关 键 词：曲司氯铵 膀胱痉挛 手术 

分 类 号：R969.3[医药卫生—药理学] R983[医药卫生—药学]