扩张型心肌病左室心肌质量与心室容积关系的研究  

Relationship of Left Ventricular Mass and Volume in Dilated Cardiomyopathy

作　　者：刘雪玲[1] 吴棘[2] 伍业冬[1] 骆峰[1] 雷蓓[1] 

机构地区：[1]广西中医学院第一附属医院超声科,南宁市530023 [2]广西医科大学第一附属医院超声诊断科

出　　处：《中国超声医学杂志》2009年第8期755-757,共3页Chinese Journal of Ultrasound in Medicine

基　　金：广西科学基金资助项目（No.桂科攻0235024-4）

摘　　要：目的探讨扩张型心肌病（DCM）左室心肌质量与心室容积关系。 方法运用M型、二维、实时三维超声心动图检测DCM患者及健康志愿者室间隔、左室后壁厚度及相对室壁厚度（即室壁厚度与左室舒张末内径的比值）、左室心肌质量（LVM）及左室心肌质量指数（LVMI）与左室舒张末容积（LVVd）及左室舒张末容积指数（LVVdI）的比值,分析DCM患者室壁厚度与左室内径、左室心肌质量指数与左室舒张末容积指数的关系。 结果DCM患者室间隔及左室壁厚度与正常人比较无明显差异,但其与左室内径的比值与正常人比较减小,左室心肌质量指数和左室舒张末容积指数都较正常人显著增加,而左室心肌质量指数与左室容积指数之比较正常人降低。 结论扩张型心肌病患者室壁相对变薄,左室心肌质量指数与左室容积指数之比较正常人降低,反映了扩张型心肌病心肌细胞肥大是以长径增大为主。超声心动图技术尤其是实时三维超声心动图能较准确测量左室心肌质量和左室容积,因而能反映扩张型心肌病左室心肌质量与心室容积的关系。Objective To investigate the relationship of left ventricular mass and left ventricular volume in dilated cardiomyopathy.Methods A total of 51 patients with dilated cardiomyopathy（DCM） and 33 healthy individuals were involved in this study.The thickness of interventricular septum（IVST） and left ventricular posterior wall（LVPWT）,left ventricular end diastolic dimension（LVDd）,left ventricular mass（LVM）,left ventricular mass index（LVMI）,left ventricular end diastolic volume（LVVd） and left ventricular end diastolic volume index（LVVdI） were measured by M-mode,two-dimensional（2D） and Real-time three-dimensional echocardiography（RT-3DE）.The ratio of IVST/LVDd,LVPWT/LVDd LVMI/LVVdI were calculated and compared between DCM and normal subjects.Results The thickness of IVST and LVPWT had no significant differences between DCM and normal subjects,but IVST/LVDd and LVPWT/LVDd were markedly decreased in DCM group.LVMI and LVVdI were higher in DCM group than in normal,however,LVMI/LVVdI was significantly lower.Conclusions As to enlarged left ventricular chamber,ventricular wall became thin in DCM.The depression of LVMI/LVVdI suggested that lengthening of myocyte was the main way of ventricular myocyte hypertrophy in dilated cardiomyopathy.Three-dimensional echocardiography can measured left ventricular mass and left ventricular volume accurately so that can reflect the relation of these two parameters in dilated cardiomyopathy.

关 键 词：扩张型心肌病 左室心肌质量 左室容积 

分 类 号：R692.5[医药卫生—泌尿科学] R542.2[医药卫生—外科学]