QTVI结合腺苷负荷超声心动图评估冠心病心肌纵向收缩功能  

Evaluation of Left Ventricular Regional Long Axis Systolic Function by Quantitative Tissue Velocity Imaging and Adenosine Stress Echocardiography

作　　者：王蓓[1] 许亮[2] 赵敏[2] 刘小明[2] 翁轶南[2] 谷莹[2] 赵博文[1] 

机构地区：[1]浙江大学医学院附属邵逸夫医院超声科 浙江大学邵逸夫临床医学研究所,杭州市310016 [2]杭州市第一人民医院超声影像科

出　　处：《中国超声医学杂志》2009年第8期769-772,共4页Chinese Journal of Ultrasound in Medicine

基　　金：浙江省医药卫生科学研究基金项目（No.2007B175）

摘　　要：目的联合使用腺苷负荷试验（ASE）与定量组织速度成像技术（QTVI）对冠心病局部纵向心肌的收缩功能进行定量分析,为临床诊断冠心病提供可靠的超声定量方法。 方法对55例疑诊冠心病者进行腺苷负荷超声心动图检查。对基础状态和负荷6min时所测得的心肌收缩期峰值（Vs）和达峰时间（TQ-S）进行统计学分析。 结果51例完成检查的患者中30例冠状动脉造影（coronary angiography,CAG）阳性,21例阴性。负荷后,对照组Vs增大（P〈0.05）,与静息状态比较,有显著性差异,TQ-S、Tei无显著性差异;冠心病组缺血节段Vs值降低（P〈0.05）,与静息状态比较,无显著性差异,TQ-S值延长,Tei值增大（P〈0.05）,有显著性差异。负荷后,冠心病组缺血节段与非缺血节段及对照组相应节段比较,Vs、TQ-S、Tei有显著性差异（P〈0.05）。 结论QTVI与ASE相结合可精确地评价局部纵向心肌收缩功能,Vs、TQ-s、Tei可作为ASE诊断冠心病的量化指标,提高超声诊断冠心病的早期检出率,并可评估冠心病纵行心肌的局部收缩功能状态。为冠心病局部心肌功能异常的超声诊断提供了新的定量分析方法。Objective To evaluate left ventricular regional systolic function of long axis by quantitative tissue velocity imaging（QTVI）and adenosine stress echocardiography（ASE）.Methods ASE was performed in 55 patients who may have coronary artery disease（CAD）.Statistic analysis of QTVI indices included peak velocity of systolic wave（Vs）and time to peak velocity（TQ-s）which were measured in the stage of baseline and 6 minutes after ASE.Results ASE showed 30 patients with coronary artery disease,each of which had at least one coronary artery≥50% stenosis and 21 healthy controls.At peak,compared with baseline,all segments of normal controls（normal group）had significantly increased Vs（P〈0.05）.There was no significant difference between TQ-sand Tei.Ischemia segments with CAD had delayed TQ-s（P〈0.05）and increased Tei-index（P〈0.05）.Conclusions QTVI and ASE can correctly evaluate left ventricular regional systolic function of long axis and detect ischemic myocardium.

关 键 词：负荷 超声心动描记术 冠状动脉疾病 定量组织速度成像 左心室局部收缩功能 

分 类 号：R541.4[医药卫生—心血管疾病] R541.404[医药卫生—内科学]